Evidence map›Paper›PMID 35046958›Full record

ArticleFrontiers in immunology2021

Spatial and Temporal Heterogeneity of Tumor-Infiltrating Lymphocytes in Advanced Urothelial Cancer.

Sandra van Wilpe, Mark A J Gorris, Lieke L van der Woude, Shabaz Sultan, Rutger H T Koornstra, Antoine G van der Heijden, Winald R Gerritsen, Michiel Simons, I Jolanda M de Vries, Niven Mehra

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Sandra van WilpeDepartment of Medical Oncology, Radboud University Medical Center, Nijmegen, Netherlands.
Mark A J GorrisDepartment of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.
Lieke L van der WoudeDepartment of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.
Shabaz SultanDepartment of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.
Rutger H T KoornstraDepartment of Medical Oncology, Rijnstate Hospital, Arnhem, Netherlands.
Antoine G van der HeijdenDepartment of Urology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.
Winald R GerritsenDepartment of Medical Oncology, Radboud University Medical Center, Nijmegen, Netherlands.
Michiel SimonsDepartment of Pathology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.
I Jolanda M de VriesDepartment of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.
Niven MehraDepartment of Medical Oncology, Radboud University Medical Center, Nijmegen, Netherlands.
Radboud University Medical Center · NLRadboud University Nijmegen · NLRadboud Institute for Molecular Life Sciences · NLRijnstate Hospital · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Checkpoint inhibitors targeting PD-(L)1 induce objective responses in 20% of patients with metastatic urothelial cancer (UC). CD8

Indexed as

AdultAgedAntineoplastic AgentsCarcinoma, Transitional CellFemaleHumansLymphocytes, Tumor-InfiltratingMaleMiddle AgedUrologic NeoplasmsAntineoplastic Agentsbiomarkerslongitudinal changesspatial heterogeneitytumor-infiltrating lymphocytesurothelial cancer

Identifiers

PMID35046958
PMCPMC8761759
OpenAlexW4206289143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.