Evidence map›Paper›PMID 35046896›Full record

ArticleFrontiers in endocrinology2021

Association Between Serum Furin and Fasting Glucose: A Cross-Sectional Study in Chinese Adults.

Yan He, Hanyun Zhu, Min Zhang, Jing Li, Shengqi Ma, Yin Lu, Linan Chen, Mingzhi Zhang, Hao Peng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. The Functions of SARS-CoV-2 Receptors in Diabetes-Related Severe COVID-19.International journal of molecular sciences · 2024
    Review
  2. Review
  3. Functional Roles of Furin in Cardio-Cerebrovascular Diseases.ACS pharmacology & translational science · 2024
    Review
  4. Review
  5. Frontiers in endocrinology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yan HeDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Hanyun ZhuDepartment of Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou, China.
Min ZhangCentral Office, Suzhou National New and Hi-Tech Industrial Development Zone Center for Disease Control and Prevention, Suzhou, China.
Jing LiDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Shengqi MaDepartment of Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou, China.
Yin LuDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Linan ChenDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Mingzhi ZhangDepartment of Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou, China.
Hao PengDepartment of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China.
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Furin has been associated with glucose metabolic phenotypes in small sampled clinical studies. However, this association has not yet been studied in Chinese. Here, we aimed to examine the association between serum furin and fasting glucose in Chinese adults. Methods: Serum furin and fasting plasma glucose were assayed for 2,172 participants (mean aged 53 years, 38% men) in the Gusu cohort. A median regression model was applied to examine the association between serum furin and fasting glucose, adjusting for age, sex, education level, cigarette smoking, alcohol drinking, obesity, blood pressure, and lipids. To facilitate data interpretation, the association between serum furin and prevalent diabetes was also examined. Results: Serum furin was negatively associated with fasting glucose (β=-0.18, Conclusions: Serum furin was negatively associated with prediabetes and diabetes in Chinese adults. Our findings suggest that serum furin may be a risk factor or a biomarker of diabetes.

Indexed as

Blood GlucoseChinaCross-Sectional StudiesFastingFemaleFurinHumansMaleMiddle AgedBlood GlucoseFurinChinesecross-sectional studydiabetesfasting plasma glucosefurinrisk factor

Identifiers

PMID35046896
PMCPMC8761844
OpenAlexW4205923502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.