Evidence map›Paper›PMID 35046892›Full record

ArticleFrontiers in endocrinology2021

Baf45a Mediated Chromatin Remodeling Promotes Transcriptional Activation for Osteogenesis and Odontogenesis.

Theodore Busby, Yuechuan Chen, Tanner C Godfrey, Mohammad Rehan, Benjamin J Wildman, Caris M Smith, Quamarul Hassan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Theodore BusbyRNA Biology and Epigenetics Laboratory, Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Alabama, Birmingham, AL, United States.
Yuechuan ChenRNA Biology and Epigenetics Laboratory, Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Alabama, Birmingham, AL, United States.
Tanner C GodfreyRNA Biology and Epigenetics Laboratory, Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Alabama, Birmingham, AL, United States.
Mohammad RehanRNA Biology and Epigenetics Laboratory, Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Alabama, Birmingham, AL, United States.
Benjamin J WildmanRNA Biology and Epigenetics Laboratory, Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Alabama, Birmingham, AL, United States.
Caris M SmithRNA Biology and Epigenetics Laboratory, Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Alabama, Birmingham, AL, United States.
Quamarul HassanRNA Biology and Epigenetics Laboratory, Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Alabama, Birmingham, AL, United States.
University of Alabama · US

Funding

Dental Academic Research Training Program (DART)T90DE022736 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Amjad Javed · 2012 to 2026
$6.7M
An Epigenetic Axis in Bone FormationR01AR069578 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HASSAN, QUAMARUL · 2016 to 2020
$1.6M
The Role of Baf45a in Bone FormationF30DE027280 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GODFREY, TANNER COLE · 2018 to 2021
$201k
NIAMS NIH HHS R01 AR069578NIDCR NIH HHS F30 DE027280NIDCR NIH HHS T90 DE022736
6 · The paper itself

Abstract

Chromatin remodeling, specifically the tissue-specific regulation in mineralized tissues, is an understudied avenue of gene regulation. Here we show that

Indexed as

Chromatin Assembly and DisassemblyTranscriptional ActivationAnimalsCells, CulturedFemaleMaleMice, TransgenicOdontogenesisOsteogenesisBaf45aBrg1/Smarca4chromatin remodelingdentinogenesisosteoblastogenesisPBAF complex

Identifiers

PMID35046892
PMCPMC8762305
OpenAlexW4206048672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.