Evidence map›Paper›PMID 35046841›Full record

ArticleFrontiers in physiology2021

Acute Kidney Injury Biomarkers and Hydration Outcomes at the Boston Marathon.

Whitley C Atkins, Cory L Butts, Melani R Kelly, Chris Troyanos, R Mark Laursen, Andrew Duckett, Dawn M Emerson, Megan E Rosa-Caldwell, Brendon P McDermott

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Biomarkers of organ stress and injury following the Boston Marathon.Journal of applied physiology (Bethesda, Md. : 1985) · 2025
    Article
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  6. Review
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  12. Ultra-Endurance Participation and Acute Kidney Injury: A Narrative Review.International journal of environmental research and public health · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Whitley C AtkinsExercise Science Research Center, College of Education and Health Professions, University of Arkansas, Fayetteville, AR, United States.
Cory L ButtsDepartment of Exercise and Nutrition Sciences, Weber State University, Ogden, UT, United States.
Melani R KellyDepartment of Exercise Science and Pre-Health Professions, Creighton University, Omaha, NE, United States.
Chris TroyanosMedical Coordinator for the Boston Marathon, Boston, MA, United States.
R Mark LaursenSargent College of Health and Rehabilitation Sciences, Boston University, Boston, MA, United States.
Andrew DuckettAthletic Training Department, Boston University, Boston, MA, United States.
Dawn M EmersonUniversity of Kansas Medical Center, Department of Physical Therapy, Rehabilitation Science, and Athletic Training, Kansas City, KS, United States.
Megan E Rosa-CaldwellDepartment of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Brendon P McDermottExercise Science Research Center, College of Education and Health Professions, University of Arkansas, Fayetteville, AR, United States.
Boston University · USUniversity of Arkansas at Fayetteville · USCreighton University · USHarvard University · USMarathon Oil (United States) · USUniversity of Kansas Medical Center · USWeber State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of our field study was to investigate the effects of running the Boston Marathon on acute kidney injury (AKI) biomarkers. We hypothesized that biomarker values would be elevated immediately post-marathon but would resolve in the 24-h post-marathon. Secondarily, we sought to identify sex differences related to renal stress. Participants were 65 runners who completed the Boston Marathon (46 ± 9 years, 65.4 ± 10.8 kg). Urine samples were collected at three different time points (pre-marathon, post-marathon, and 24-h post-marathon). Blood samples were collected post-marathon and 24-h post-marathon. Urine specific gravity (USG) and AKI biomarkers were evaluated. Pre-marathon USG (1.012 ± 0.007) was significantly less than post-marathon (1.018 ± 0.008) and 24-h post-marathon (1.020 ± 0.009;

Indexed as

dehydrationendurance sportsmarathon-runningrenal stresssex-differences

Identifiers

PMID35046841
PMCPMC8761943
OpenAlexW4206247899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.