Evidence map›Paper›PMID 35046820›Full record

ReviewFrontiers in pharmacology2021

Production of Bovine Colostrum for Human Consumption to Improve Health.

Merve Kaplan, Ayşenur Arslan, Hatice Duman, Melda Karyelioğlu, Barış Baydemir, Bilgetekin Burak Günar, Merve Alkan, Ayşe Bayraktar, Halil İbrahim Tosun, Melih Ertürk and 5 more

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Lactoperoxidase: Properties, Functions, and Potential Applications.International journal of molecular sciences · 2025
    Review
  12. Lactoferrin: Properties and Potential Uses in the Food Industry.International journal of molecular sciences · 2025
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Antimicrobial Properties of Colostrum and Milk.Antibiotics (Basel, Switzerland) · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Merve KaplanDepartment of Molecular Biology and Genetics, Canakkale Onsekiz Mart University, Canakkale, Turkey.
Ayşenur ArslanDepartment of Molecular Biology and Genetics, Canakkale Onsekiz Mart University, Canakkale, Turkey.
Hatice DumanDepartment of Molecular Biology and Genetics, Canakkale Onsekiz Mart University, Canakkale, Turkey.
Melda KaryelioğluDepartment of Molecular Biology and Genetics, Canakkale Onsekiz Mart University, Canakkale, Turkey.
Barış BaydemirDepartment of Coaching Education, Canakkale Onsekiz Mart University, Canakkale, Turkey.
Bilgetekin Burak GünarDepartment of Physical Education and Sports Teaching, Canakkale Onsekiz Mart University, Canakkale, Turkey.
Merve AlkanDepartment of Molecular Biology and Genetics, Canakkale Onsekiz Mart University, Canakkale, Turkey.
Ayşe BayraktarDepartment of Molecular Biology and Genetics, Canakkale Onsekiz Mart University, Canakkale, Turkey.
Halil İbrahim TosunUluova Dairy, Canakkale, Turkey.
Melih ErtürkUluova Dairy, Canakkale, Turkey.
Günay EskiciDepartment of Coaching Education, Canakkale Onsekiz Mart University, Canakkale, Turkey.
Rebbeca M DuarEvolve Biosystems, Inc., Davis, CA, United States.
Bethany M HenrickEvolve Biosystems, Inc., Davis, CA, United States.
Steven A FreseDepartment of Nutrition, University of Nevada Reno, Reno, NV, United States.
Sercan KaravDepartment of Molecular Biology and Genetics, Canakkale Onsekiz Mart University, Canakkale, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colostrum contains all essential nutrients for the neonate during the first days of life, with impacts that continue far beyond these first days. Bovine colostrum has been used for human consumption due to the high concentrations of bioactive proteins, vitamins, minerals, growth factors, as well as free and conjugated oligosaccharides. Processes involved in the preparation of bovine colostrum for human consumption play a pivotal role in preserving and maintaining the activity of the bioactive molecules. As bovine colostrum is a multifunctional food that offers a myriad of benefits for human health, assessing the main processes used in preparing it with both advantages and disadvantages is a crucial point to discuss. We discuss major processes effects for colostrum production on the nutritional value, some advanced technologies to preserve processed bovine colostrum and the end-product forms consumed by humans whether as dairy products or dietary supplements.

Indexed as

bovine colostrumdrying methodshuman consumptionimmunoglobulinsliposomal technologynanotechnologythermal processing

Identifiers

PMID35046820
PMCPMC8762312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.