Evidence map›Paper›PMID 35046796›Full record

ArticleFrontiers in pharmacology2021

Ginsenoside Rb1 Attenuates Triptolide-Induced Cytotoxicity in HL-7702 Cells

Hulinyue Peng, Longtai You, Chunjing Yang, Kaixin Wang, Manting Liu, Dongge Yin, Yuchen Xu, Xiaoxv Dong, Xingbin Yin, Jian Ni

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
6.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hulinyue PengSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Longtai YouSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Chunjing YangDepartment of Pharmacy, Beijing Shijitan Hospital Affiliated to Capital University of Medical Sciences, Beijing, China.
Kaixin WangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Manting LiuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Dongge YinSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Yuchen XuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Xiaoxv DongSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Xingbin YinSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Jian NiSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Beijing University of Chinese Medicine · CNBeijing Shijitan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triptolide (TP) is the major bioactive compound extracted from

Indexed as

apoptosiscytotoxicityginsenoside Rb1HL-7702 cellsKeap1/Nrf2/ARE pathwaytriptolide

Identifiers

PMID35046796
PMCPMC8762226
OpenAlexW4206610946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.