Evidence map›Paper›PMID 35046767›Full record

ArticleFrontiers in neuroscience2021

The Therapeutic and Diagnostic Potential of Amyloid β Oligomers Selective Antibodies to Treat Alzheimer's Disease.

Kirsten L Viola, Maira A Bicca, Adrian M Bebenek, Daniel L Kranz, Vikas Nandwana, Emily A Waters, Chad R Haney, Maxwell Lee, Abhay Gupta, Zachary Brahmbhatt and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Serotonergic Regulation in Alzheimer's Disease.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Inhibition of amyloid beta oligomer accumulation by NU-9: A unifying mechanism for the treatment of neurodegenerative diseases.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Behaviour Hallmarks in Alzheimer's Disease 5xFAD Mouse Model.International journal of molecular sciences · 2024
    Review
  13. Anti-amyloid Antibody Therapies for Alzheimer's Disease.Nuclear medicine and molecular imaging · 2024
    Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Anti-Amyloid Immunotherapies for Alzheimer's Disease: A 2023 Clinical Update.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Kirsten L ViolaDepartment of Neurobiology, Northwestern University, Evanston, IL, United States.
Maira A BiccaDepartment of Neurobiology, Northwestern University, Evanston, IL, United States.
Adrian M BebenekIllinois Mathematics and Science Academy, Aurora, IL, United States.
Daniel L KranzDepartment of Neurobiology, Northwestern University, Evanston, IL, United States.
Vikas NandwanaDepartment of Materials Science and Engineering, Northwestern University, Evanston, IL, United States.
Emily A WatersCenter for Advanced Molecular Imaging, Northwestern University, Evanston, IL, United States.
Chad R HaneyCenter for Advanced Molecular Imaging, Northwestern University, Evanston, IL, United States.
Maxwell LeeDepartment of Neurobiology, Northwestern University, Evanston, IL, United States.
Abhay GuptaIllinois Mathematics and Science Academy, Aurora, IL, United States.
Zachary BrahmbhattIllinois Mathematics and Science Academy, Aurora, IL, United States.
Weijian HuangDepartment of Neurobiology, Northwestern University, Evanston, IL, United States.
Ting-Tung ChangSmall Animal Imaging Facility, Van Andel Research Institute, Grand Rapids, MI, United States.
Anderson PeckSmall Animal Imaging Facility, Van Andel Research Institute, Grand Rapids, MI, United States.
Clarissa ValdezDepartment of Neurobiology, Northwestern University, Evanston, IL, United States.
Vinayak P DravidIllinois Mathematics and Science Academy, Aurora, IL, United States.
William L KleinDepartment of Neurobiology, Northwestern University, Evanston, IL, United States.
Northwestern University · USIllinois Mathematics and Science Academy · USVan Andel Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Improvements have been made in the diagnosis of Alzheimer's disease (AD), manifesting mostly in the development of

Indexed as

5xFADAlzheimer’s diseaseAβ oligomersdiagnosticsMRIPETtherapeutics

Identifiers

PMID35046767
PMCPMC8761808
OpenAlexW4206071654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.