Evidence map›Paper›PMID 35046672›Full record

ArticleInfection and drug resistance2022

The Genomic Characterization of KPC-Producing

Yingying Du, Shikui Mu, Yan Liu, Yinghua Yuan, Yunlou Zhu, Lijie Ma, Qixing Wang, Zhengfang Zhu, Yuhao Liu, Sheng Wang

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and drug resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03950544 (How to Optimize the Combined Antibiotic Therapy for Carbapenem Resistant Klebsiella Pneumoniae), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03950544 early_phase1unknown statusnot on this map

How to Optimize the Combined Antibiotic Therapy for Carbapenem Resistant Klebsiella Pneumoniae

TypeinterventionalSponsorShanghai 10th People's HospitalRan2019 to 2020Enrolled80ConditionsAntibiotic Resistant InfectionArmsFosfomycin, Tigecycline, Polymyxin B
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yingying Du *Department of Critical Care Medicine, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai, 200072, People's Republic of China.
Shikui Mu *Department of Critical Care Medicine, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai, 200072, People's Republic of China.ORCID 0000-0002-7048-7905
Yan LiuDepartment of Clinical Microbiology, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai, 200072, People's Republic of China.ORCID 0000-0002-3183-5698
Yinghua YuanDepartment of Clinical Microbiology, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai, 200072, People's Republic of China.
Yunlou ZhuDepartment of Clinical Microbiology, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai, 200072, People's Republic of China.
Lijie MaDepartment of Clinical Microbiology, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai, 200072, People's Republic of China.
Qixing WangDepartment of Clinical Microbiology, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai, 200072, People's Republic of China.
Zhengfang ZhuDepartment of Clinical Microbiology, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai, 200072, People's Republic of China.
Yuhao LiuDepartment of Critical Care Medicine, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai, 200072, People's Republic of China.
Sheng WangDepartment of Critical Care Medicine, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai, 200072, People's Republic of China.ORCID 0000-0003-3439-4696
Shanghai Tenth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study retrospectively analyzed the genome characteristics of

methodsFrom February 2018 to December 2019, 36 strains of multidrug-resistant

resultsThe distribution of resistance and virulence genes had little difference, but most strains had significant differences in the plasmid-encoded region. Most strains (31/36) carried the carbapenemase gene

conclusionThe CLINICAL TRIALS REGISTRATION: Clinical Trials.gov Identifier: NCT03950544.

Indexed as

blaKPC-2drug-resistant plasmidsKlebsiella pneumoniaesingle nucleotide polymorphismwhole-genome sequencing

Identifiers

PMID35046672
PMCPMC8760991
OpenAlexW4205136114

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.