ArticleJournal of asthma and allergy2022
Burden of Pertussis in Individuals with a Diagnosis of Asthma: A Retrospective Database Study in England.
Article in Journal of asthma and allergy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Immunogenicity and safety of reduced-antigen tetanus, diphtheria and acellular pertussis vaccination in adults treated for obstructive airway diseases.Human vaccines & immunotherapeutics · 2023Pooled it
- A budget impact analysis of adult immunization with tetanus, diphtheria, and pertussis vaccination for the prevention of pertussis in at-risk populations in Colombia.Human vaccines & immunotherapeutics · 2025Article
- The Burden of Pertussis Disease and Vaccination Coverage in Australian Adults Attending Primary Health Care.Vaccines · 2025Article
- Clinical and Epidemiological Characteristics of Pediatric Pertussis Cases: A Retrospective Study from Southeast Romania.Antibiotics (Basel, Switzerland) · 2025Article
- Public health management of pertussis in adults: Practical challenges and future strategies.Human vaccines & immunotherapeutics · 2024Review
- Seroepidemiology of pertussis immunity in five provinces of China: A population-based, cross-sectional study.Human vaccines & immunotherapeutics · 2024Article
- Understanding the impact of adult pertussis and current approaches to vaccination: A narrative review and expert panel recommendations.Human vaccines & immunotherapeutics · 2024Review
- Epidemiology of Pertussis and Pertussis-Related Complications in Adults: A German Claims Data Analysis.Infectious diseases and therapy · 2024Article
- Population-Based Study of Pertussis Incidence and Risk Factors among Persons >50 Years of Age, Australia.Emerging infectious diseases · 2024Observational
- Burden of Pertussis in Adults Aged 50 Years and Older: A Retrospective Database Study in England.Infectious diseases and therapy · 2023Article
- Vaccination against Community-Acquired Pneumonia in Spanish Adults: Practical Recommendations by the NeumoExperts Prevention Group.Antibiotics (Basel, Switzerland) · 2023Review
- Available evidence and potential for vaccines for reduction in antibiotic prescriptions.Human vaccines & immunotherapeutics · 2022Article
- Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe impact of pertussis in individuals with asthma is not fully understood. We estimated the incidence, health care resource utilization (HCRU), and direct medical costs (DMC) of pertussis in patients with asthma. PATIENTS AND
methodsIn this retrospective cohort study, the incidence rate of pertussis (identified using diagnostic codes) among individuals aged ≥50 years with an asthma diagnosis was assessed during 2009-2018 using Clinical Practice Research Datalink and Hospital Episode Statistics databases. HCRU and DMC were compared - between patients with diagnoses of asthma and pertussis (asthma+/pertussis+) and propensity score-matched patients with a diagnosis of asthma without pertussis (asthma+/pertussis-) - in the months around the pertussis diagnosis (-6 to +11).
resultsAmong 687,105 individuals, 346 had a reported pertussis event (incidence rate: 9.6/100,000 person-years of follow-up; 95% confidence interval: 8.6-10.7). HCRU and DMC were assessed among 314 asthma+/pertussis+ patients and 1256 matched asthma+/pertussis- controls. Baseline HCRU was similar in both cohorts, but increases were observed in the asthma+/pertussis+ cohort from -6 to -1 month before to 2-5 months after diagnosis. Rates of accident and emergency visits, general practitioner (GP)/nurse visits, and GP prescriptions were 4.3-, 3.1-, and 1.3-fold, respectively, in the asthma+/pertussis+ vs asthma+/pertussis- cohorts during the month before diagnosis; GP/nurse visit rates were 2.0- and 1.2-fold during 0-2 and 2-5 months after diagnosis, respectively (all
conclusionA pertussis diagnosis among adults aged ≥50 years with asthma resulted in significant increases in HCRU and DMC across several months around diagnosis, suggesting lengthy diagnosis times and highlighting the need for prevention strategies.
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