Evidence map›Paper›PMID 35046627›Full record

ArticleWorld journal of gastroenterology2021

Life prognosis of sentinel node navigation surgery for early-stage gastric cancer: Outcome of lymphatic basin dissection.

Shinichi Kinami, Naohiko Nakamura, Tomoharu Miyashita, Hidekazu Kitakata, Sachio Fushida, Takashi Fujimura, Yasuo Iida, Noriyuki Inaki, Toru Ito, Hiroyuki Takamura

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Guideline
  2. Feasibility of intraoperative pathologic examination for sentinel lymph nodes during sentinel node navigation surgery in early gastric cancer: results of pathologic protocol for SENORITA trial.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2024
    Trial
  3. Review
  4. [Practice and reflection on sentinel lymph node navigation surgery for early gastric cancer].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Function-preserving gastrectomy based on the sentinel node concept prevents osteosarcopenia in patients with gastric cancer.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Gastric cancer surgery in South Korea: Past, present, and future.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2023
    Article
  16. Review
  17. Endoscopic fluorescent lymphography for gastric cancer.World journal of gastrointestinal endoscopy · 2023
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Shinichi KinamiDepartment of Surgical Oncology, Kanazawa Medical University, Kahoku 920-0293, Ishikawa, Japan. kinami@kanazawa-med.ac.jp.
Naohiko NakamuraDepartment of Surgical Oncology, Kanazawa Medical University, Kahoku 920-0293, Ishikawa, Japan.
Tomoharu MiyashitaDepartment of Surgical Oncology, Kanazawa Medical University, Kahoku 920-0293, Ishikawa, Japan.
Hidekazu KitakataDepartment of Gastroenterological Endoscopy, Kanazawa Medical University, Kahoku 920-0293, Ishikawa, Japan.
Sachio FushidaDepartment of Gastrointestinal Surgery, Kanazawa University, Kanazawa 920-8641, Ishikawa, Japan.
Takashi FujimuraDepartment of Surgery, Toyama City Hospital, Toyama 939-8511, Toyama, Japan.
Yasuo IidaDepartment of Mathematics, Division of General Education, Kanazawa Medical University, Kahoku 920-0293, Ishikawa, Japan.
Noriyuki InakiDepartment of Gastrointestinal Surgery, Kanazawa University, Kanazawa 920-8641, Ishikawa, Japan.
Toru ItoDepartment of Gastroenterological Endoscopy, Kanazawa Medical University, Kahoku 920-0293, Ishikawa, Japan.
Hiroyuki TakamuraDepartment of Surgical Oncology, Kanazawa Medical University, Kahoku 920-0293, Ishikawa, Japan.
Kanazawa Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLymphatic basin dissection is a sentinel node biopsy method that is specific for gastric cancer. In this method, the dyed lymphatic system is dissected

aimTo investigate the life prognosis of SNNS for gastric cancer in comparison with guidelines surgery.

methodsThis was a retrospective cohort study. Patients were selected from gastric cancer patients who underwent sentinel node biopsy from April 1999 to March 2016. Patients from April 1999 to August 2008 were from the Department of Surgery II, Kanazawa University Hospital, and patients from August 2009 to March 2016 were from the Department of Surgical Oncology, Kanazawa Medical University Hospital. Patients who were diagnosed with gastric cancer, which was preoperatively diagnosed as superficial type (type 0), 5 cm or less in length, clinical T1-2 and node negative, and underwent various gastrectomies guided by sentinel node navigation were retrospectively collected. The overall survival (OS) and relapse-free survival (RFS) of these patients (SNNS group) were investigated. Patients with gastric cancer of the same stage and who underwent guidelines gastrectomy with standard nodal dissection were also selected as the control group.

resultsA total of 239 patients in the SNNS group and 423 patients in the control group were included. Pathological nodal metastasis was observed in 10.5% and 10.4% of the SNNS and control groups, respectively. The diagnostic abilities of sentinel node biopsy were 84% and 98.6% for sensitivity and accuracy, respectively. In the SNNS group, 81.6% of patients underwent modified gastrectomy or function-preserving curative gastrectomy with lymphatic basin dissection, in which the extent of nodal dissection was further reduced compared to the guidelines. The OS rate in the SNNS group was 96.8% at 5 years and was significantly better than 91.3% in the control group (

conclusionThe oncological safety of patients who undergo gastrectomy guided by sentinel node navigation is not inferior to that of the guidelines surgery.

Indexed as

Stomach NeoplasmsDissectionGastrectomyHumansLymph Node ExcisionNeoplasm Recurrence, LocalPrognosisRetrospective StudiesSentinel Lymph Node BiopsyEarly gastric cancerFunction preserving surgeryGastrectomyLymphatic basin dissectionLymph node dissectionSentinel node biopsy

Identifiers

PMID35046627
PMCPMC8678813
OpenAlexW4200173042

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.