Evidence map›Paper›PMID 35046511›Full record

ArticleScientific reports2022

Contrasting maternal and paternal genetic histories among five ethnic groups from Khyber Pakhtunkhwa, Pakistan.

Muhammad Tariq, Habib Ahmad, Brian E Hemphill, Umar Farooq, Theodore G Schurr

Open access · goldAbstract read
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Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Muhammad TariqCentre for Omic Sciences, Islamia College, Peshawar, 25120, Khyber Pakhtunkhwa, Pakistan. mtariq@icp.edu.pk.
Habib AhmadDepartment of Genetics, Hazara University Mansehra, Mansehra, 21120, Pakistan.
Brian E HemphillDepartment of Anthropology, University of Alaska, Fairbanks, AK, 99775, USA.
Umar FarooqCollege of Life Science, Northeast Forestry University, Harbin, 150040, China.
Theodore G SchurrDepartment of Anthropology, University of Pennsylvania, 3260 South Street, Philadelphia, PA, 19104-6398, USA. tgschurr@sas.upenn.edu.
Hazara University · PKIslamia College University · PKNortheast Forestry University · CNUniversity of Alaska Fairbanks · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Northwest Pakistan has served as a point of entry to South Asia for different populations since ancient times. However, relatively little is known about the population genetic history of the people residing within this region. To better understand human dispersal in the region within the broader history of the subcontinent, we analyzed mtDNA diversity in 659 and Y-chromosome diversity in 678 individuals, respectively, from five ethnic groups (Gujars, Jadoons, Syeds, Tanolis and Yousafzais), from Swabi and Buner Districts, Khyber Pakhtunkhwa Province, Pakistan. The mtDNAs of all individuals were subject to control region sequencing and SNP genotyping, while Y-chromosomes were analyzed using 54 SNPs and 19 STR loci. The majority of the mtDNAs belonged to West Eurasian haplogroups, with the rest belonging to either South or East Asian lineages. Four of the five Pakistani populations (Gujars, Jadoons, Syeds, Yousafzais) possessed strong maternal genetic affinities with other Pakistani and Central Asian populations, whereas one (Tanolis) did not. Four haplogroups (R1a, R1b, O3, L) among the 11 Y-chromosome lineages observed among these five ethnic groups contributed substantially to their paternal genetic makeup. Gujars, Syeds and Yousafzais showed strong paternal genetic affinities with other Pakistani and Central Asian populations, whereas Jadoons and Tanolis had close affinities with Turkmen populations from Central Asia and ethnic groups from northeast India. We evaluate these genetic data in the context of historical and archeological evidence to test different hypotheses concerning their origins and biological relationships.

Indexed as

Genetics, PopulationChromosomes, Human, YDNA, MitochondrialEthnicityHaplotypesHumansMalePakistanPhylogenyPolymorphism, Single NucleotideDNA, Mitochondrial

Identifiers

PMID35046511
PMCPMC8770644
OpenAlexW4206167823

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