Evidence map›Paper›PMID 35046432›Full record

ArticleScientific reports2022

A new detection model of microaneurysms based on improved FC-DenseNet.

Zhenhua Wang, Xiaokai Li, Mudi Yao, Jing Li, Qing Jiang, Biao Yan

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

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  12. Automatic Detection of Microaneurysms in OCT Images Using Bag of Features.Computational and mathematical methods in medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Zhenhua Wang *College of Information Science, Shanghai Ocean University, Shanghai, 201306, China.
Xiaokai Li *College of Information Science, Shanghai Ocean University, Shanghai, 201306, China.
Mudi Yao *The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, 211166, China.
Jing Li *The Affiliated Sixth People's Hospital, Shanghai Jiaotong University, Shanghai, 200233, China.
Qing JiangThe Affiliated Eye Hospital, Nanjing Medical University, Nanjing, 211166, China. jiangqin710@126.com.
Biao YanEye Institute, Eye and ENT Hospital, Shanghai Medical College, Fudan University, Shanghai, 200030, China. yanbiao1982@hotmail.com.
Nanjing Medical University · CNShanghai Ocean University · CNEye & ENT Hospital of Fudan University · CNShanghai Sixth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic retinopathy (DR) is a frequent vascular complication of diabetes mellitus and remains a leading cause of vision loss worldwide. Microaneurysm (MA) is usually the first symptom of DR that leads to blood leakage in the retina. Periodic detection of MAs will facilitate early detection of DR and reduction of vision injury. In this study, we proposed a novel model for the detection of MAs in fluorescein fundus angiography (FFA) images based on the improved FC-DenseNet, MAs-FC-DenseNet. FFA images were pre-processed by the Histogram Stretching and Gaussian Filtering algorithm to improve the quality of FFA images. Then, MA regions were detected by the improved FC-DenseNet. MAs-FC-DenseNet was compared against other FC-DenseNet models (FC-DenseNet56 and FC-DenseNet67) or the end-to-end models (DeeplabV3+ and PSPNet) to evaluate the detection performance of MAs. The result suggested that MAs-FC-DenseNet had higher values of evaluation metrics than other models, including pixel accuracy (PA), mean pixel accuracy (MPA), precision (Pre), recall (Re), F1-score (F1), and mean intersection over union (MIoU). Moreover, MA detection performance for MAs-FC-DenseNet was very close to the ground truth. Taken together, MAs-FC-DenseNet is a reliable model for rapid and accurate detection of MAs, which would be used for mass screening of DR patients.

Indexed as

Fluorescein AngiographyImage Processing, Computer-AssistedModels, TheoreticalDiabetic RetinopathyHumansMass ScreeningMicroaneurysm

Identifiers

PMID35046432
PMCPMC8770497
OpenAlexW4206159774

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.