Evidence map›Paper›PMID 35046412›Full record

ArticleNature communications2022

Structure of a type IV secretion system core complex encoded by multi-drug resistance F plasmids.

Xiangan Liu, Pratick Khara, Matthew L Baker, Peter J Christie, Bo Hu

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Type IV Secretion System Drives Lipid Mixing.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Subdomains of theLife science alliance · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Comparative Analysis of T4SS Molecular Architectures.Journal of microbiology and biotechnology · 2023
    Review
  12. Article
  13. Role of the CagY antenna projection inInfection and immunity · 2023
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xiangan Liu *Department of Microbiology and Molecular Genetics, McGovern Medical School, 6431 Fannin St, Houston, TX, 77030, USA.
Pratick Khara *Department of Microbiology and Molecular Genetics, McGovern Medical School, 6431 Fannin St, Houston, TX, 77030, USA.
Matthew L BakerDepartment of Biochemistry and Molecular Biology, McGovern Medical School, 6431 Fannin St, Houston, TX, 77030, USA.
Peter J ChristieDepartment of Microbiology and Molecular Genetics, McGovern Medical School, 6431 Fannin St, Houston, TX, 77030, USA. Peter.J.Christie@uth.tmc.edu.ORCID http://orcid.org/0000-0002-9799-7067
Bo HuDepartment of Microbiology and Molecular Genetics, McGovern Medical School, 6431 Fannin St, Houston, TX, 77030, USA. Bo.Hu@uth.tmc.edu.ORCID http://orcid.org/0000-0002-9117-879X
The University of Texas Health Science Center · US

Funding

TRANSLOCATION OF DNA ACROSS THE AGROBACTERIUM ENVELOPER01GM048746 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI CHRISTIE, PETER J. · 1998 to 2018
$6.9M
Biological And Structural Diversity Of Bacterial Type IV Secretion SystemsR35GM131892 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI PETER j. CHRISTIE · 2019 to 2026
$3.8M
In Situ Architecture of Specialized Bacterial Secretion SystemsR35GM138301 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI HU, BO · 2020 to 2024
$2.0M
Structure analysis of F pilus biogenesisR21AI142378 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI HU, BO · 2019 to 2020
$424k
NIAID NIH HHS R21 AI142378NIGMS NIH HHS R01 GM048746NIGMS NIH HHS R35 GM131892NIGMS NIH HHS R35 GM138301
6 · The paper itself

Abstract

Bacterial type IV secretion systems (T4SSs) are largely responsible for the proliferation of multi-drug resistance. We solved the structure of the outer-membrane core complex (OMCC

Indexed as

Drug Resistance, Multiple, BacterialCell MembraneEscherichia coliEscherichia coli ProteinsF FactorModels, MolecularType IV Secretion SystemsEscherichia coli ProteinsType IV Secretion Systems

Identifiers

PMID35046412
PMCPMC8770708
OpenAlexW4205278795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.