ArticleAnnals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia2022
Hemoadsorption of Rivaroxaban and Ticagrelor during Acute Type A Aortic Dissection Operations.
Article in Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Optimal management of cardiac surgery patients using direct oral anticoagulants: recommendations for clinical practice.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2023Pooled it
- Efficacy of CytoSorb®: a systematic review and meta-analysis.Critical care (London, England) · 2023Pooled it
- Antibiotics and Other Drugs Removal by the CytoSorbAntibiotics (Basel, Switzerland) · 2026Review
- Potential Clinical Use of CytoSorbLife (Basel, Switzerland) · 2025Article
- 2024 EACTS/EACTAIC Guidelines on patient blood management in adult cardiac surgery in collaboration with EBCP.Interdisciplinary cardiovascular and thoracic surgery · 2025Article
- 2024 EACTS/EACTAIC Guidelines on patient blood management in adult cardiac surgery in collaboration with EBCP.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025Article
- The use of CytoSorb hemoadsorption in critically ill patients: a narrative review.Frontiers in medicine · 2025Review
- Antithrombotic drug removal with hemoadsorption during off-pump coronary artery bypass grafting.Journal of cardiothoracic surgery · 2024Article
- A Contemporary Review of the Use of Extracorporeal CytoSorbJournal of clinical medicine · 2024Review
- [Hemoperfusion in anesthesia and intensive care medicine: benefits, risks, and evidence for different systems].Die Anaesthesiologie · 2023Review
- Intraoperative ticagrelor removal via hemoadsorption during on-pump coronary artery bypass grafting.JTCVS open · 2023Article
- Cost-Effectiveness and Budget Impact of a Novel Antithrombotic Drug Removal System to Reduce Bleeding Risk in Patients on Preoperative Ticagrelor Undergoing Cardiac Surgery.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2023Article
- The use of CytoSorb® in a prasugrel-loaded patient undergoing emergent coronary artery bypass graft surgery.Clinical case reports · 2023Article
- Pharmacokinetics of immunosuppressive agents during hemoperfusion in a sheep model.Frontiers in medicine · 2023Article
- Perioperative hemostatic management of patients with type A aortic dissection.Frontiers in cardiovascular medicine · 2023Review
- StandardizedFrontiers in cardiovascular medicine · 2023Article
- Antithrombotic drug removal from whole blood using Haemoadsorption with a porous polymer bead sorbent.European heart journal. Cardiovascular pharmacotherapy · 2022Article
- A New Apheresis Device for Antithrombotic Drug Removal during Off-Pump Coronary Artery Bypass Surgery.Medicina (Kaunas, Lithuania) · 2022Article
- Removal of Apixaban during Emergency Cardiac Surgery Using Hemoadsorption with a Porous Polymer Bead Sorbent.Journal of clinical medicine · 2022Article
- Management of perioperative bleeding risk in patients on antithrombotic medications undergoing cardiac surgery-a systematic review.Journal of thoracic disease · 2022Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo analyze the results of hemoadsorption in patients with cardiac surgery to thoracic aortic surgery, who had been loaded beforehand with either Factor Xa inhibitor rivaroxaban or P2Y12 receptor antagonist ticagrelor.
methodsWe investigated 21 of 171 consecutive patients (median age 71 [interquartile range 62, 76] years) who underwent emergency cardiac operations for acute type A aortic dissection between 2014 and 2020. These patients were pretreated with rivaroxaban (n = 9) or ticagrelor (n = 12). In ten of 21 cases (since 2017), we installed a hemoadsorber into the heart-lung machine and compared the results to eleven patients done without hemoadsorber before that time.
resultsThe operation time was significantly shorter in the adsorber group (286 ± 40 min vs. 348 ± 79 min; p = 0.045). The postoperative 24-hour drainage volume was significantly lower after adsorption (p <0.001; 482 ± 122 ml vs. 907 ± 427 ml) and no rethoracotomy had to be performed (compared to two rethoracotomies [18.9%] among patients without adsorber use). Also, patients without hemoadsorption required significantly more platelet transfusions (p = 0.049).
conclusionsIn patients with acute type A aortic dissection who were pretreated with rivaroxaban and ticagrelor, the intraoperative use of CytoSorb hemoadsorption during cardiopulmonary bypass is reported for the first time. The method was found to be effective to prevent from bleeding and to improve the outcome in aortic dissection.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.