Evidence map›Paper›PMID 35046022›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Spatiotemporal analysis identifies ABF2 and ABF3 as key hubs of endodermal response to nitrate.

Orlando Contreras-López, Elena A Vidal, Eleodoro Riveras, José M Alvarez, Tomás C Moyano, Erin E Sparks, Joaquín Medina, Angelo Pasquino, Philip N Benfey, Gloria M Coruzzi and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Antagonistic regulation of nitrogen and drought signaling mediated by NIN-like protein 7 transcription factor inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Orlando Contreras-LópezFondo de Desarrollo de Areas Prioritarias, Center for Genome Regulation, 8370415 Santiago, Chile.ORCID 0000-0002-4048-6637
Elena A VidalAgencia Nacional de Investigación y Desarrollo-Millennium Science Initiative Program, Millennium Institute for Integrative Biology, 7500565 Santiago, Chile.ORCID 0000-0002-8208-7327
Eleodoro RiverasFondo de Desarrollo de Areas Prioritarias, Center for Genome Regulation, 8370415 Santiago, Chile.ORCID 0000-0001-8924-3954
José M AlvarezAgencia Nacional de Investigación y Desarrollo-Millennium Science Initiative Program, Millennium Institute for Integrative Biology, 7500565 Santiago, Chile.
Tomás C MoyanoFondo de Desarrollo de Areas Prioritarias, Center for Genome Regulation, 8370415 Santiago, Chile.
Erin E SparksDepartment of Plant and Soil Sciences, Delaware Biotechnology Institute, University of Delaware, Newark, DE 19713.ORCID 0000-0003-1543-6950
Joaquín MedinaCentro de Biotecnología y Genómica de Plantas, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, Universidad Politécnica de Madrid, 28040 Madrid, Spain.ORCID 0000-0002-1735-330X
Angelo PasquinoCenter for Genomics and Systems Biology, New York University, New York, NY 10003.ORCID 0000-0003-1715-0892
Philip N BenfeyDepartment of Biology, Duke University, Durham, NC 27708.ORCID 0000-0001-5302-758X
Gloria M CoruzziCenter for Genomics and Systems Biology, New York University, New York, NY 10003.ORCID 0000-0003-2608-2166
Rodrigo A GutiérrezFondo de Desarrollo de Areas Prioritarias, Center for Genome Regulation, 8370415 Santiago, Chile; rgutierrez@bio.puc.cl.ORCID 0000-0002-5961-5005
Pontificia Universidad Católica de Chile · CLNew York University · USUniversidad Mayor · CLBiotechnology Institute · USDuke University · USInstituto Nacional de Investigación y Tecnología Agraria y Alimentaria · ES

Funding

Hit-and-Run transcription: The impact of transient interactions in dynamic gene regulatory networks that mediate rapid nutrient signalingR01GM121753 · NIGMS · NEW YORK UNIVERSITY · PI CORUZZI, GLORIA, SHASHA, DENNIS ELLIOTT · 2020 to 2023
$1.7M
A Molecular Genetic Analysis of Root MorphogenesisR35GM131725 · NIGMS · DUKE UNIVERSITY · PI BENFEY, PHILIP N · 2019 to 2023
$1.5M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM121753NIGMS NIH HHS R35 GM131725
6 · The paper itself

Abstract

Nitrate is a nutrient and a potent signal that impacts global gene expression in plants. However, the regulatory factors controlling temporal and cell type-specific nitrate responses remain largely unknown. We assayed nitrate-responsive transcriptome changes in five major root cell types of the

Indexed as

Gene Expression Regulation, PlantPlant Physiological PhenomenaArabidopsisArabidopsis ProteinsBasic-Leucine Zipper Transcription FactorsComputational BiologyDNA-Binding ProteinsGene Expression ProfilingGene OntologyGene Regulatory NetworksModels, BiologicalNitratesOrgan SpecificityPlant RootsTranscription FactorsTranscriptomeABF3 protein, ArabidopsisArabidopsis ProteinsAt1g45249 protein, ArabidopsisBasic-Leucine Zipper Transcription FactorsDNA-Binding ProteinsNitratesTranscription Factorscell-specificnitrate signalingtranscriptional regulation

Identifiers

PMID35046022
PMCPMC8794810
OpenAlexW4205210899

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.