Evidence map›Paper›PMID 35045977›Full record

ArticleGenome research2022

Distal regulation, silencers, and a shared combinatorial syntax are hallmarks of animal embryogenesis.

Paola Cornejo-Páramo, Kathrein Roper, Sandie M Degnan, Bernard M Degnan, Emily S Wong

Open access · hybridAbstract read
In one paragraph

Article in Genome research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  5. The Function and Regulation of celsr1a in Skeletal Age-associated Homeostasis and Repair in Zebrafish.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  6. Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Paola Cornejo-PáramoVictor Chang Cardiac Research Institute, Sydney 2010, Australia.
Kathrein RoperSchool of Biological Sciences, University of Queensland, Brisbane 4072, Australia.
Sandie M DegnanSchool of Biological Sciences, University of Queensland, Brisbane 4072, Australia.ORCID 0000-0001-8003-0426
Bernard M DegnanSchool of Biological Sciences, University of Queensland, Brisbane 4072, Australia.
Emily S WongVictor Chang Cardiac Research Institute, Sydney 2010, Australia.ORCID 0000-0003-0315-2942
The University of Queensland · AUVictor Chang Cardiac Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The chromatin environment plays a central role in regulating developmental gene expression in metazoans. Yet, the ancestral regulatory landscape of metazoan embryogenesis is unknown. Here, we generate chromatin accessibility profiles for six embryonic, plus larval and adult stages in the sponge

Indexed as

ChromatinHistone CodeAnimalsDNAEmbryonic DevelopmentGene Expression Regulation, DevelopmentalProtein BindingChromatinDNA

Identifiers

PMID35045977
PMCPMC8896464
OpenAlexW4220785243

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.