Evidence map›Paper›PMID 35045816›Full record

ArticleBMC medical imaging2022

Vessel segmentation for X-ray coronary angiography using ensemble methods with deep learning and filter-based features.

Zijun Gao, Lu Wang, Reza Soroushmehr, Alexander Wood, Jonathan Gryak, Brahmajee Nallamothu, Kayvan Najarian

Abstract read
In one paragraph

Article in BMC medical imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

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14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
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  10. Patient-specificFrontiers in cardiovascular medicine · 2024
    Review
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  12. [Research progress on image-based calculation of coronary artery fractional flow reserve].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023
    Article
  13. Review
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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Zijun Gao *Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, USA. zijung@umich.edu.
Lu Wang *Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, USA.
Reza SoroushmehrDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, USA.
Alexander WoodDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, USA.
Jonathan GryakDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, USA.
Brahmajee NallamothuDepartment of Internal Medicine, University of Michigan, Ann Arbor, USA.
Kayvan NajarianDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAutomated segmentation of coronary arteries is a crucial step for computer-aided coronary artery disease (CAD) diagnosis and treatment planning. Correct delineation of the coronary artery is challenging in X-ray coronary angiography (XCA) due to the low signal-to-noise ratio and confounding background structures.

methodsA novel ensemble framework for coronary artery segmentation in XCA images is proposed, which utilizes deep learning and filter-based features to construct models using the gradient boosting decision tree (GBDT) and deep forest classifiers. The proposed method was trained and tested on 130 XCA images. For each pixel of interest in the XCA images, a 37-dimensional feature vector was constructed based on (1) the statistics of multi-scale filtering responses in the morphological, spatial, and frequency domains; and (2) the feature maps obtained from trained deep neural networks. The performance of these models was compared with those of common deep neural networks on metrics including precision, sensitivity, specificity, F1 score, AUROC (the area under the receiver operating characteristic curve), and IoU (intersection over union).

resultsWith hybrid under-sampling methods, the best performing GBDT model achieved a mean F1 score of 0.874, AUROC of 0.947, sensitivity of 0.902, and specificity of 0.992; while the best performing deep forest model obtained a mean F1 score of 0.867, AUROC of 0.95, sensitivity of 0.867, and specificity of 0.993. Compared with the evaluated deep neural networks, both models had better or comparable performance for all evaluated metrics with lower standard deviations over the test images.

conclusionsThe proposed feature-based ensemble method outperformed common deep convolutional neural networks in most performance metrics while yielding more consistent results. Such a method can be used to facilitate the assessment of stenosis and improve the quality of care in patients with CAD.

Indexed as

Deep LearningCoronary AngiographyCoronary DiseaseCoronary VesselsHumansImage Processing, Computer-AssistedDeep learningEnsemble learningMedical image segmentationX-ray coronary angiography

Identifiers

PMID35045816
PMCPMC8767756

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.