Trial reportBMC pregnancy and childbirth2022
Comparison of the effectiveness of virtual reality and chewing mint gum on labor pain and anxiety: a randomized controlled trial.
Trial report in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Effectiveness of Virtual Reality for Pain Relief in Procedures Related to Obstetrics and Gynaecology: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.BJOG : an international journal of obstetrics and gynaecology · 2026Pooled it
- Digital technology-assisted labor support in delivery rooms on maternal pain and anxiety: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- The effect of virtual reality on pregnant women and fetuses: a systematic review and meta-analysis of randomized controlled trials.Archives of gynecology and obstetrics · 2025Pooled it
- Effectiveness of virtual reality therapy in the treatment of anxiety disorders in adolescents and adults: a systematic review and meta-analysis of randomized controlled trials.Frontiers in psychiatry · 2025Pooled it
- Efficacy of virtual reality for pain relief in medical procedures: a systematic review and meta-analysis.BMC medicine · 2024Pooled it
- The Effect of Chewing Gum in Managing Labor Pain Intensity and Anxiety Level in Primiparous Women: A Randomized Controlled Trial.International journal of community based nursing and midwifery · 2025Trial
- No pain relief by virtual reality during hysterosalpingography (HSG): results from a randomized controlled trial.Human reproduction (Oxford, England) · 2024Trial
- Reducing pain and anxiety with virtual reality in (outpatient) gynecological procedures: a systematic review with meta-analysis.AJOG global reports · 2026Review
- Effectiveness of chewing gum on blood glucose level among pregnant women with gestational diabetes: a randomized controlled clinical trial.Diabetology & metabolic syndrome · 2026Article
- The Effect of Chewing Gum on Anxiety and Labor Pain: A Systematic Review and Meta-Analysis.Health science reports · 2025Review
- Effectiveness of an immersive virtual reality intervention to reduce anxiety during pregnancy: a quasiexperimental single-group pre-post study.BMC pregnancy and childbirth · 2025Article
- Exploring the Efficacy of Virtual Reality Training in Obstetric Procedures and Patient Care-A Systematic Review.Healthcare (Basel, Switzerland) · 2025Review
- Effect of lite touch on the anxiety of low-risk pregnant women in the latent phase of childbirth: a randomized controlled trial.Frontiers in psychology · 2024Article
- Virtual reality in managing dental pain and anxiety: a comprehensive review.Frontiers in medicine · 2023Review
- Patient perceptions of virtual reality for pain relief in labor: A qualitative study.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
- Investigating the Effect of Chewing Gum on Head, Neck, and Facial Edema in Burn Patients: Doubled-blinded Randomized Controlled Trial.Iranian journal of nursing and midwifery researchArticle
- Comparison of the Efficacy of Virtual Reality Glasses versus Mint Gum for Pain and Anxiety Relief During Episiotomy Repair: A Randomized Clinical Trial.Iranian journal of nursing and midwifery researchArticle
- Virtual Reality as a Nonpharmacological Tool for Acute Pain Management: A Scoping Review.Innovations in clinical neuroscienceReview
- Virtual reality interventions designed to support parents during and throughout the first year after birth: A scoping review.Digital healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveChildbirth pain and anxiety are often unnatural, as opposed to being one of the most practical ways to use non-pharmacological methods. The aim of this study was to compare the effectiveness of virtual reality and chewing mint gum on childbirth pain and anxiety.
methodsThis is a single-blind, three-group clinical trial study on 93 mothers referred to Allameh Bohlool Gonabadi and Sajjadieh Torbate Jam Hospitals for natural childbirth in 2018-2019. Subjects were randomly divided into three groups of chewing gum, virtual reality, and control using six blocks. Chewing gum interventions in one group and virtual reality in the other group were performed twice in 4-5 cm and 7-8 cm dilatations for 20 min. In the control group, no intervention except routine care was performed. The research tools included Visual Analogue Scale of Pain and Spielberger's Anxiety Inventory. Data were analyzed using SPSS) version 22(, ANOVA, Kruskal-Wallis, Chi-square and Tukey tests. Significance level was considered 0.05 in this study.
resultsThe main result was differences in pain and anxiety before and after the intervention. There was no significant difference between pre-intervention pain and anxiety scores in the three groups, but there was a significant difference between pain and anxiety scores immediately and 30 min after the intervention.
conclusionThe results of this study showed that virtual reality and chewing mint gum intervention reduce pain and anxiety in the first stage of childbirth.
trial registrationIRCT20181214041963N1 .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.