Evidence map›Paper›PMID 35045807›Full record

ArticleBMC pediatrics2022

The effect of COVID-19 lockdown on the glycemic control of children with type 1 diabetes.

Elina Hakonen, Tero Varimo, Anna-Kaisa Tuomaala, Päivi J Miettinen, Mari-Anne Pulkkinen

Open access · goldAbstract read
In one paragraph

Article in BMC pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Tubeless Insulin Pump Combined with a Cloud-Based Data Management Platform: Real-World Evidence from 14,765 French People with Diabetes.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Endocrine manifestations of COVID-19 in children: A scoping review.Best practice & research. Clinical endocrinology & metabolism · 2023
    Article
  10. Article
  11. Impact of COVID-19 pandemic on HbAAdvances in laboratory medicine · 2023
    Article
  12. Article
  13. Sustained Improvement in Glycemic Control in Emerging Adults with Type 1 Diabetes 2 Years After the Start of the COVID-19 Pandemic.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2023
    Article
  14. Article
  15. Diabetes and COVID-19: Short- and Long-Term Consequences.Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2022
    Review
  16. Telemedicine for the Clinical Management of Diabetes; Implications and Considerations After COVID-19 Experience.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Elina HakonenPediatric Research Center, New Children's Hospital, Helsinki University Hospital, Stenbäckinkatu 9, HUS 00029, PO Box 347, Helsinki, Finland. elina.hakonen@helsinki.fi.ORCID 0000-0002-9652-3724
Tero VarimoPediatric Research Center, New Children's Hospital, Helsinki University Hospital, Stenbäckinkatu 9, HUS 00029, PO Box 347, Helsinki, Finland.
Anna-Kaisa TuomaalaPediatric Research Center, New Children's Hospital, Helsinki University Hospital, Stenbäckinkatu 9, HUS 00029, PO Box 347, Helsinki, Finland.
Päivi J MiettinenPediatric Research Center, New Children's Hospital, Helsinki University Hospital, Stenbäckinkatu 9, HUS 00029, PO Box 347, Helsinki, Finland.
Mari-Anne PulkkinenPediatric Research Center, New Children's Hospital, Helsinki University Hospital, Stenbäckinkatu 9, HUS 00029, PO Box 347, Helsinki, Finland.
Helsinki University Hospital · FIUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBetween March 18

methodsIn this retrospective register study from a pediatric diabetes outpatient clinic, we analyzed the glycemic data of T1D patients (n = 245; aged 4 to 16 years) before and under the lockdown. All the participants used continuous glucose monitoring (rtCGM or iCGM), two-thirds were on insulin pumps (CSII), and one-third on multiple daily insulin injections (MDI) therapy.

resultsIn our patient cohort, time in range (TIR, n = 209) and mean glucose levels (n = 214) were similar prior to and under the lockdown (mean change 0.44% [95%CI: -1.1-2.0], p = 0.56 and -0.13 mmol/mol [95%CI: -0.3-0.1], p = 0.17, respectively). However, children treated with CSII improved their glycemic control significantly during the lockdown: TIR improved on average 2.4% [0.6-4.2] (p = 0.010) and mean blood glucose level decreased -0.3 mmol/mol [-0.6-(-0.1)] (p = 0.008). The difference was more pronounced in girls, adolescents and patients using conventional insulin pumps.

conclusionsThe glycemic control in T1D children did not deteriorate under the lockdown, and patients on CSII even improved their control, which suggests that social distancing might have allowed families to use the insulin pump more accurately as out-of-home activities were on hold.

Indexed as

COVID-19Diabetes Mellitus, Type 1AdolescentBlood GlucoseBlood Glucose Self-MonitoringChildCommunicable Disease ControlFemaleGlycemic ControlHumansHypoglycemic AgentsPandemicsRetrospective StudiesSARS-CoV-2Blood GlucoseHypoglycemic AgentsChildren and adolescentsContinuous glucose monitoringCOVID-19 lockdownGlycemic controlType 1 diabetes

Identifiers

PMID35045807
PMCPMC8766349
OpenAlexW4205139030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.