Evidence map›Paper›PMID 35045720›Full record

ArticleStroke2022

Inpatient Management of Acute Stroke of Unknown Type in Resource-Limited Settings.

Morgan L Prust, Deanna Saylor, Stanley Zimba, Fred Stephen Sarfo, Gentle S Shrestha, Aaron Berkowitz, Nirali Vora

Open access · hybridAbstract read
In one paragraph

Article in Stroke, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Targeting Neurovascular Pathways: Gene Therapy as a Novel Treatment for Vascular Dementia After Stroke.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Diversity, equity and inclusion in neurology.Nature reviews. Neurology · 2024
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Long-term determinants of death after stroke in Ghana: Analysis by stroke types & subtypes.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 4 countries.

Morgan L PrustYale School of Medicine, New Haven, CT (M.L.P.).ORCID 0000-0002-1380-3422
Deanna SaylorJohns Hopkins University Hospital, Baltimore, MD (D.S.).ORCID 0000-0002-9297-0244
Stanley ZimbaUniversity Teaching Hospital, Lusaka, Zambia (D.S., S.Z.).ORCID 0000-0001-6861-6416
Fred Stephen SarfoKwame Nkrumah University of Science & Technology, Kumasi, Ghana (F.S.S.).ORCID 0000-0001-7274-5093
Gentle S ShresthaTribhuvan University Teaching Hospital, Kathmandu, Nepal (G.S.S.).ORCID 0000-0003-0385-2340
Aaron Berkowitz *Kaiser Permanente Bernard J Tyson School of Medicine, Pasadena, CA (A.B.).
Nirali Vora *Stanford University Medical Center, CA (N.V.).ORCID 0000-0002-7362-5509
University Teaching Hospital · ZMKaiser Permanente · USKwame Nkrumah University of Science and Technology · GHStanford University · USTribhuvan University Teaching Hospital · NPYale University · US

Funding

Adaptation and Implementation of Clinical Practice Guidelines to Improve Stroke Outcomes in ZambiaK01TW011771 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SAYLOR, DEANNA RAE · 2021 to 2025
$1.1M
Understanding hydration and stroke outcomes in ZambiaR21NS118543 · NINDS · JOHNS HOPKINS UNIVERSITY · PI BAHOUTH, MONA N · 2020 to 2021
$354k
FIC NIH HHS K01 TW011771NINDS NIH HHS R21 NS118543
6 · The paper itself

Abstract

Stroke is the second leading cause of death and disability worldwide, with a disproportionate burden on low- and middle-income countries. Critical elements of guideline-based stroke care developed in high-income countries are not applicable to resource-limited settings, where lack of access to neuroimaging prevents clinicians from distinguishing between ischemic stroke and intracranial hemorrhage, requiring challenging clinical decision-making, particularly in the acute setting. We discuss strategies for acute inpatient management of stroke of unknown type with a focus on blood pressure management and antiplatelet therapy when neuroimaging is unavailable, and review some of the challenges and strategies for successfully implementing stroke unit care in resource-limited health care settings.

Indexed as

Blood PressureBrainClinical Decision-MakingHumansInpatientsNeuroimagingStrokeblood pressurecause of deathclinical decision-makinginpatientneuroimaging

Identifiers

PMID35045720
PMCPMC8885836
OpenAlexW4205554815

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.