Evidence map›Paper›PMID 35045694›Full record

Trial reportHaematologica2022

T-cell immune responses following vaccination with mRNA BNT162b2 against SARS-CoV-2 in patients with chronic lymphocytic leukemia: results from a prospective open-label clinical trial.

Lisa Blixt, David Wullimann, Soo Aleman, Jeanette Lundin, Puran Chen, Yu Gao, Angelica Cuapio, Mira Akber, Joshua Lange, Olga Rivera-Ballesteros and 4 more

Abstract readClinical Trial
In one paragraph

Trial report in Haematologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Lisa BlixtDept of Hematology, Karolinska University Hospital Solna, Stockholm, Sweden; Dept of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
David WullimannCenter for Infectious Medicine, Dept of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
Soo AlemanDepartment of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden; Department of Medicine Huddinge, Infectious Diseases, Karolinska Institutet, Stockholm, Sweden.
Jeanette LundinDept of Hematology, Karolinska University Hospital Solna, Stockholm, Sweden; Dept of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Puran ChenCenter for Infectious Medicine, Dept of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
Yu GaoCenter for Infectious Medicine, Dept of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
Angelica CuapioCenter for Infectious Medicine, Dept of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
Mira AkberCenter for Infectious Medicine, Dept of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
Joshua LangeCenter for Infectious Medicine, Dept of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
Olga Rivera-BallesterosCenter for Infectious Medicine, Dept of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
Marcus BuggertCenter for Infectious Medicine, Dept of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
Hans-Gustaf LjunggrenCenter for Infectious Medicine, Dept of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
Lotta HanssonDept of Hematology, Karolinska University Hospital Solna, Stockholm, Sweden; Dept of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden. lotta.hansson@regionstockholm.se.
Anders ÖsterborgDept of Hematology, Karolinska University Hospital Solna, Stockholm, Sweden; Dept of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19Leukemia, Lymphocytic, Chronic, B-CellAntibodies, ViralBNT162 VaccineHumansImmunityProspective StudiesRNA, MessengerSARS-CoV-2T-LymphocytesVaccinationAntibodies, ViralBNT162 VaccineRNA, Messenger

Identifiers

PMID35045694
PMCPMC8968881

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.