Evidence map›Paper›PMID 35045307›Full record

ArticleCell reports2022

R-type voltage-gated Ca

Jonathan G Murphy, Jakob J Gutzmann, Lin Lin, Jiahua Hu, Ronald S Petralia, Ya-Xian Wang, Dax A Hoffman

Abstract read
In one paragraph

Article in Cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Characterization of Three Distinct Loss-of-Function Cav2.3 Variants.International journal of molecular sciences · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Kv4.2 Regulates Basal Synaptic Strength by Inhibiting R-Type Calcium Channels in the Hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  7. Neuroplasticity in the transition from acute to chronic pain.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
    Review
  8. Design of Ultrapotent Genetically Encoded Inhibitors of Kv4.2 for Gating Neural Plasticity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Jonathan G MurphyMolecular Neurophysiology and Biophysics Section, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: jonathan.murphy@nih.gov.
Jakob J GutzmannMolecular Neurophysiology and Biophysics Section, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Lin LinMolecular Neurophysiology and Biophysics Section, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Jiahua HuMolecular Neurophysiology and Biophysics Section, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Ronald S PetraliaAdvanced Imaging Core, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD 20892, USA.
Ya-Xian WangAdvanced Imaging Core, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD 20892, USA.
Dax A HoffmanMolecular Neurophysiology and Biophysics Section, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: hoffmand@mail.nih.gov.
Eunice Kennedy Shriver Center · USInstitute of Molecular Biology and Biophysics · RUNational Institute on Deafness and Other Communication Disorders · USNational Institutes of Health · US

Funding

Potassium Channels and Dendritic Function in Hippocampal Pyramidal NeuronsZIAHD008755 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI HOFFMAN, DAX A · 2009 to 2025
$29.6M
Advanced Imaging CoreZICDC000081 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI WINKLER, DENNIS · 2012 to 2025
$17.4M
Regulation of local translation in neuronal dendrites of a mouse model of Fragile X SyndromeFI2GM120004 · NIGMS · U.S. NATIONAL INST/CHILD HLTH/HUMAN DEV · PI MURPHY, JONATHAN G · 2016 to 2016
–
Intramural NIH HHS ZIA HD008755Intramural NIH HHS ZIC DC000081NIGMS NIH HHS FI2 GM120004
6 · The paper itself

Abstract

The subthreshold voltage-gated transient K

Indexed as

AnimalsCalcium Channels, R-TypeDendritesHEK293 CellsHippocampusHumansMiceMice, Inbred C57BLNeuronal PlasticityRatsRats, Sprague-DawleyShal Potassium ChannelsSynaptic TransmissionCalcium Channels, R-TypeShal Potassium ChannelsCa(2+) channeldendritehippocampusK(+) channelspinesynapse

Identifiers

PMID35045307
PMCPMC10496648
OpenAlexW4225906590

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.