ArticlePLoS medicine2022
Reporting bias in clinical trials: Progress toward transparency and next steps.
Article in PLoS medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Reported outcome measures in necrotising soft tissue infections: a systematic review.Diving and hyperbaric medicine · 2024Pooled it
- Detecting and Mitigating Bias for Inclusive and Trustworthy Clinical Research: A Scientific Statement From the American Heart Association.Circulation. Genomic and precision medicine · 2026Review
- Targeting urological cancers with CAR-T cell therapy: current landscape and future directions.Journal of translational medicine · 2026Review
- The Outcome and Impact of Academic Cancer Clinical Trials with Participation from Canadian Sites (2015-2024).Cancers · 2025Article
- Preferred Reporting Items for Microbiotherapy (PRIM) Guidelines Across Medical Disciplines: An International Delphi Consensus.Journal of gastroenterology and hepatology · 2025Review
- Review
- Predicting accrual success for better clinical trial resource allocation.Scientific reports · 2025Article
- Child public health interventions for conflict-affected populations: A systematic review.PLOS global public health · 2025Article
- Dissemination and outcome reporting bias in clinical malaria intervention trials: a cross-sectional analysis.Malaria journal · 2024Article
- Ethical Considerations in the Design and Conduct of Clinical Trials of Artificial Intelligence.JAMA network open · 2024Article
- Secondary Endpoint Utilization and Publication Rate among Phase III Oncology Trials.Cancer research communications · 2024Article
- The transparency of reporting 'harms' encountered with the surgically assisted acceleration of orthodontic tooth movement in the published randomized controlled trials: a meta-epidemiological study.Progress in orthodontics · 2023Review
- Reading Between the Lines: Navigating Nuance in Medical Literature to Optimize Clinical Decision-Making and Health Care Outcomes.Advances in medical education and practice · 2023Review
- Authors reply: comments on the published meta-analysis of antibiotic resistance in hospital-acquired ESKAPE-E infections in low- and lower-middle-income countries.Emerging microbes & infections · 2022Article
- Global challenges in preparedness and response to epidemic infectious diseases.Molecular therapy : the journal of the American Society of Gene Therapy · 2022Review
- Improving the methodological quality of randomized clinical trials assessing psychotherapy for borderline personality disorder: Recommendations for the future.Frontiers in psychiatry · 2022Article
- Do retinal implants provide long-term efficacy, safety and improve quality of life? A systematic review.Therapeutic advances in ophthalmologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mayookha Mitra-Majumdar and Aaron Kesselheim reflect on steps taken to combat reporting bias in clinical trials over the last two decades.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.