ArticleAmerican journal of respiratory and critical care medicine2022
Hypoxia Increases the Potential for Neutrophil-mediated Endothelial Damage in Chronic Obstructive Pulmonary Disease.
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In one paragraph
Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- Automatically titrating oxygen system versus constant flow oxygen system during exercise in patients with COPD: a systematic review and meta-analysis.BMC pulmonary medicine · 2025Pooled it
- Biologics in Older Adults with Chronic Obstructive Pulmonary Disease: A Narrative Review.Journal of clinical medicine · 2026Review
- Correlation between urea-to-creatinine ratio and poor prognosis of intensive care unit patients with chronic obstructive pulmonary disease: a study based on the MIMIC-IV database.BMC pulmonary medicine · 2026Article
- Hypoxia or tobacco-smoke exposure induce region-specific microvascular remodeling in the brain.Scientific reports · 2026Article
- Dysregulated iron metabolism associates with neutrophilic airway inflammation in COPD.Clinical science (London, England : 1979) · 2026Article
- Systemic inflammatory markers predict mortality in autoimmune thyroiditis: threshold-driven risk stratification and prognostic insights from a nationwide cohort.Hormones (Athens, Greece) · 2026Article
- Beyond the Lungs: A Narrative Review of Cardiopulmonary Risk Reduction and Management Perspectives in Thai COPD Patients.International journal of chronic obstructive pulmonary disease · 2026Review
- Impact of intranasal cigarette smoke exposure on murine peripheral immune responses and lung pathology.Frontiers in toxicology · 2026Article
- Development and validation of a nomogram based on immune-inflammation-nutrition indictors for predicting 28-day mortality in sepsis patients with severe fungal pneumonia.Frontiers in cellular and infection microbiology · 2026Article
- Cardiopulmonary risk in the COPD patient: the EPOCONSUL audit.Scientific reports · 2025Article
- Association between systemic inflammation response index and advanced stages in U.S. cardiovascular-kidney-metabolic syndrome patients: a cross-sectional study using NHANES 2015-2020 data.BMC cardiovascular disorders · 2025Article
- COPD: the role of neutrophils in inflammation, pathophysiology, and as drug targets.Clinical science (London, England : 1979) · 2025Review
- Article
- Equine Asthma Is Characterised by Severity-Dependent Correlations Between Blood Neutrophil Cholesterol Content and NET Formation.European journal of immunology · 2025Article
- Association between blood urea nitrogen-to-albumin ratio and mortality in ICU patients with chronic obstructive pulmonary disease: data from the MIMIC IV database.BMC geriatrics · 2025Article
- Integrating Machine Learning and Multi-Omics to Explore Neutrophil Heterogeneity.Biomedicines · 2025Review
- Caspase-11 regulates systemic inflammation and cell death in a cell-specific manner after trauma with shock.Journal of leukocyte biology · 2025Article
- The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Association of altitude and eosinophil with the one-year mortality of acute exacerbation of chronic obstructive pulmonary disease: a cohort study.BMC pulmonary medicine · 2025Article
- Association between blood urea nitrogen to albumin ratio and 28-day mortality in ICU patients with acute respiratory failure: a retrospective analysis of MIMIC-IV database.BMC medical informatics and decision making · 2025Article
Corrections and comments
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Authors and funding
18 authors at 5 institutions in 1 country.
Katharine M LodgeDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-3203-9941
Arlette VassalloDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Bin LiuDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Merete LongDepartment of Infection, Immunity, and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom; and.
Zhen TongDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Paul R NewbyInstitute of Inflammation and Ageing, University of Birmingham and.
Danya Agha-JaffarNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Koralia PaschalakiNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Clara E GreenInstitute of Inflammation and Ageing, University of Birmingham and.
Kylie B R BelchamberInstitute of Inflammation and Ageing, University of Birmingham and.
Victoria C RidgerDepartment of Infection, Immunity, and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom; and.
Robert A StockleyUniversity Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
Elizabeth SapeyInstitute of Inflammation and Ageing, University of Birmingham and.
Charlotte SummersDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Andrew S CowburnNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Edwin R ChilversDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Wei LiDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Alison M CondliffeDepartment of Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
University of Cambridge · GBImperial College London · GBUniversity of Birmingham · GBUniversity Hospitals Birmingham NHS Foundation Trust · GBUniversity of Sheffield · GB
Funding
British Heart Foundation PG/12/54/29734British Heart Foundation PG/15/39/31519British Heart Foundation PG/17/1/32532British Heart Foundation PG/17/58/33134British Heart Foundation PG/19/75/34686Medical Research Council MR/M012328/2Wellcome TrustWellcome Trust 102706/Z/13/Z
Abstract
PubMed holds no abstract for this paper.
Indexed as
Pulmonary Disease, Chronic ObstructiveVascular System InjuriesEndothelial CellsHumansHypoxiaLeukocyte ElastaseNeutrophilsLeukocyte Elastasecardiovascular diseasecell degranulationneutrophil elastasevascular endothelium
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.