ArticleMethods in molecular biology (Clifton, N.J.)2022
Study of Rotary Cell Culture System-Induced Microgravity Effects on Cancer Biomarkers.
Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
- Advances in the study of gastric organoids as disease models.World journal of gastrointestinal oncology · 2024Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since humans started to explore the possibilities of life beyond earth, space missions began unmanned in the beginning and late with astronauts to explore the curiosity. There are several factors in space which are different from that of the earth's atmosphere, including gravity, cosmic radiation, extreme temperatures, and heavy ions. The space environment consists of very less gravitational force, which is often termed as microgravity. Microgravity, along with radiation in space, is known to suppress the immune system of astronauts, and hence, the chances of getting diagnosed with cancer could not be overlooked. Microgravity simulators are used to generate microgravity in laboratory conditions, and it could be a very beneficial tool to study the effect of altered gravity on various types of cells, including cancer cells. Cancer cells produce several biomarkers which are used for cancer diagnosis and prognosis. Protein biomarkers are indispensable for the ongoing fight against cancer. In this chapter, we describe the culture of both anchorage-dependent and suspension cell lines using rotary cell culture system (RCCS) to induce microgravity condition and its effect on protein biomarkers.
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Registered trials
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