Evidence map›Paper›PMID 35044644›Full record

ArticleJournal of neurovirology2022

Correlations between cerebrospinal fluid biomarkers, neurocognitive tests, and resting-state electroencephalography (rsEEG) in patients with HIV-associated neurocognitive disorders.

A Barco, S Orlando, G Stroffolini, V Pirriatore, A Lazzaro, D Vai, G Guastamacchia, G Noce, C Atzori, M Trunfio and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neurovirology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Cerebrospinal Fluid CXCL13 as Candidate Biomarker of Intrathecal Immune Activation, IgG Synthesis and Neurocognitive Impairment in People with HIV.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2023
    Article
  5. A new perspective on HIV: effects of HIV on brain-heart axis.Frontiers in cardiovascular medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

A BarcoUnit of Infectious Diseases, Department of Medical Sciences, University of Turin, Turin, Italy. ambra.barco@gmail.com.ORCID 0000-0001-6204-7179
S OrlandoUnit of Neurology, Maria Vittoria Hospital, ASL "Città Di Torino", Turin, Italy.
G StroffoliniUnit of Infectious Diseases, Department of Medical Sciences, University of Turin, Turin, Italy.
V PirriatoreUnit of Infectious Diseases, Department of Medical Sciences, University of Turin, Turin, Italy.
A LazzaroUnit of Infectious Diseases, Department of Medical Sciences, University of Turin, Turin, Italy.
D VaiUnit of Neurology, Maria Vittoria Hospital, ASL "Città Di Torino", Turin, Italy.
G GuastamacchiaUnit of Neurology, Maria Vittoria Hospital, ASL "Città Di Torino", Turin, Italy.
G NoceIRCCS SDN, Naples, Italy.
C AtzoriUnit of Neurology, Maria Vittoria Hospital, ASL "Città Di Torino", Turin, Italy.
M TrunfioUnit of Infectious Diseases, Department of Medical Sciences, University of Turin, Turin, Italy.
S BonoraUnit of Infectious Diseases, Department of Medical Sciences, University of Turin, Turin, Italy.
G Di PerriUnit of Infectious Diseases, Department of Medical Sciences, University of Turin, Turin, Italy.
A CalcagnoUnit of Infectious Diseases, Department of Medical Sciences, University of Turin, Turin, Italy.
University of Turin · ITOspedale Maria Vittoria · ITDepartment of Medical Sciences · BYSDN Istituto di Ricerca Diagnostica e Nucleare · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HIV-associated neurocognitive disorders (HAND) are highly prevalent in people living with HIV (PLWH) despite successful treatment with combination antiretroviral therapy (cART). HAND pathogenesis is complex and definitive surrogate biomarkers are not clearly defined. Brain function has been assessed through the evaluation of cortical source rhythms with delta waves associated with neurological impairment. The aim of this study was to assess the correlation between EEG cortical sources, cerebrospinal fluid (CSF) biomarkers, and neurocognitive tests in PLWH with HAND. PLWH with HAND without significant comorbidities were enrolled. Baseline rsEEG-LORETA waves, CSF biomarkers (t-tau, p-tau, β-amiloid

Indexed as

HIV InfectionsBiomarkersElectroencephalographyHumansMental Status and Dementia TestsNeopterinNeurocognitive DisordersBiomarkersNeopterinCSF biomarkersEEGHANDHIVNeopterinNeurocognitive disorders

Identifiers

PMID35044644
OpenAlexW4205706996

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.