Evidence map›Paper›PMID 35044515›Full record

ArticleSurgical endoscopy2022

Completely minimally invasive versus hybrid Ivor-Lewis oesophagectomy for oesophageal and gastro-oesophageal junctional cancer: a UK multi-centre comparative study.

Krashna Patel, Alan Askari, Omar Abbassi, Naga Venkatesh Jayanthi, Oliver Claydon, James Laycock, Aravindh Ramalingam, Bhaskar Kumar, Joshua Wong, Mohamed Aly and 2 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Krashna PatelEssex Upper GI, Regional Centre for Oesophagogastric Surgery, Broomfield Hospital, Court Road, Broomfield, Chelmsford, CM1 7ET, UK. krashna@doctors.org.uk.ORCID http://orcid.org/0000-0002-2834-4986
Alan AskariUpper GI Cancer Centre, Watford General Hospital, Vicarage Road, Watford, UK.
Omar AbbassiEssex Upper GI, Regional Centre for Oesophagogastric Surgery, Broomfield Hospital, Court Road, Broomfield, Chelmsford, CM1 7ET, UK.
Naga Venkatesh JayanthiEssex Upper GI, Regional Centre for Oesophagogastric Surgery, Broomfield Hospital, Court Road, Broomfield, Chelmsford, CM1 7ET, UK.
Oliver ClaydonThe Department of Upper Gastrointestinal (UGI) Surgery, Norfolk & Norwich University Hospital, Colney Lane, Norwich, Norfolk, UK.
James LaycockThe Department of Upper Gastrointestinal (UGI) Surgery, Norfolk & Norwich University Hospital, Colney Lane, Norwich, Norfolk, UK.
Aravindh RamalingamThe Department of Upper Gastrointestinal (UGI) Surgery, Norfolk & Norwich University Hospital, Colney Lane, Norwich, Norfolk, UK.
Bhaskar KumarThe Department of Upper Gastrointestinal (UGI) Surgery, Norfolk & Norwich University Hospital, Colney Lane, Norwich, Norfolk, UK.
Joshua WongUpper GI Cancer Centre, Watford General Hospital, Vicarage Road, Watford, UK.
Mohamed AlyUpper GI Cancer Centre, Watford General Hospital, Vicarage Road, Watford, UK.
Periyathambi JambulingamUpper GI Cancer Centre, Watford General Hospital, Vicarage Road, Watford, UK.
STEER Collaborative

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLimited robust evidence exists comparing outcomes following completely minimally invasive oesophagectomy (CMIO) to hybrid oesophagectomy (HO) in the treatment of resectable oesophageal and gastro-oesophageal junctional (GOJ) cancer. This multi-centre study aims to assess postoperative morbidity between HO and CMIO according to the full Esophagectomy Complications Consensus Group (ECCG) complication platform.

methodsAll consecutive patients undergoing an Ivor-Lewis HO or Ivor-Lewis CMIO for cancer between 2016 and 2018 in three UK tertiary centres were included. The primary study outcome was 30-day overall complications, evaluated by the ECCG complication subgroups. Secondary outcomes included survival outcomes and perioperative parameters between the two approaches.

resultsOf the 382 patients included, 228 (59.7%) patients had HOs and 154 (40.3%) patients had CMIOs with no inter-group baseline differences. Patients undergoing CMIO experienced less 30-day postoperative complications compared to those under undergoing HO (43.5% vs 57.0%, p = 0.010). ECCG defined pulmonary and infective complications were less frequent in the CMIO group. Anastomotic leak rates and oncological outcomes were similar between the two groups. Independent predictors of 30-day postoperative complications include surgical approach with HO and high ASA grade on multivariable analysis.

conclusionsIvor-Lewis CMIO demonstrates superior short-term surgical outcomes when compared to Ivor-Lewis HO with no compromise in oncological feasibility. Anastomotic leak rates were equivalent between both groups. A robust randomised controlled trial is required to validate the findings of this study.

Indexed as

Esophageal NeoplasmsStomach NeoplasmsAnastomotic LeakEsophagectomyHumansLength of StayMinimally Invasive Surgical ProceduresPostoperative ComplicationsRetrospective StudiesTreatment OutcomeUnited KingdomMinimally invasive oesophagectomyOesophageal cancerOutcomes

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.