Evidence map›Paper›PMID 35044208›Full record

ArticleJournal of virology2022

Identification of Amino Acids within Nonstructural Proteins 10 and 14 of the Avian Coronavirus Infectious Bronchitis Virus That Result in Attenuation

Sarah Keep, Phoebe Stevenson-Leggett, Giulia Dowgier, Holly Everest, Graham Freimanis, Michael Oade, John A Hammond, Maria Armesto, Rut Vila, Tura Bru and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Sarah KeepThe Pirbright Institutegrid.63622.33, Surrey, United Kingdom.ORCID 0000-0001-9583-630X
Phoebe Stevenson-LeggettThe Pirbright Institutegrid.63622.33, Surrey, United Kingdom.
Giulia DowgierThe Pirbright Institutegrid.63622.33, Surrey, United Kingdom.
Holly EverestThe Pirbright Institutegrid.63622.33, Surrey, United Kingdom.
Graham FreimanisThe Pirbright Institutegrid.63622.33, Surrey, United Kingdom.
Michael OadeThe Pirbright Institutegrid.63622.33, Surrey, United Kingdom.
John A HammondThe Pirbright Institutegrid.63622.33, Surrey, United Kingdom.
Maria ArmestoThe Pirbright Institutegrid.63622.33, Surrey, United Kingdom.
Rut VilaZoetis, VMRD, Zaventem, Belgium.
Tura BruZoetis, VMRD, Zaventem, Belgium.
Harm GeerligsZoetis, VMRD, Zaventem, Belgium.
Paul BrittonThe Pirbright Institutegrid.63622.33, Surrey, United Kingdom.
Erica BickertonThe Pirbright Institutegrid.63622.33, Surrey, United Kingdom.ORCID 0000-0002-4012-1283
The Pirbright Institute · GBZoetis (Belgium) · BE

Funding

Biotechnology and Biological Sciences Research Council BB/H01425X/1Biotechnology and Biological Sciences Research Council BBS/E/I/00001424Biotechnology and Biological Sciences Research Council BBS/E/I/00007034Biotechnology and Biological Sciences Research Council BBS/E/I/00007037Biotechnology and Biological Sciences Research Council BBS/E/I/00007038Biotechnology and Biological Sciences Research Council BBS/E/I/00007039Biotechnology and Biological Sciences Research Council BBS/E/I/COV07001UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BB/H01425X/1UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BB/L003988/1 & 1645891UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BB/P019137/1UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BBS/E/I/00001424UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BBS/E/I/00007031 & BBS/E/I/00007034 & BBS/E/I/00007037 & BBS/E/I/00007038 & BBS/E/I/00007039
6 · The paper itself

Abstract

The

Indexed as

Amino AcidsCoronavirus InfectionsInfectious bronchitis virusPoultry DiseasesViral Nonstructural ProteinsViral VaccinesAnimalsChick EmbryoChickensFemaleVaccines, AttenuatedAmino AcidsVaccines, AttenuatedViral Nonstructural ProteinsViral Vaccinesavianavian virusescoronavirusinfectious bronchitis virusreplicasereverse genetic analysisreverse geneticsvaccineveterinary vaccine development

Identifiers

PMID35044208
PMCPMC8941869
OpenAlexW4206440149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.