ArticleGenes, brain, and behavior2022
Emergent intra-pair sex differences and organized behavior in pair bonded prairie voles (Microtus ochrogaster).
Article in Genes, brain, and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 21 citations in OpenAlex.
- Acute partner loss enhances social motivation and nucleus accumbens dopamine release in prairie voles.bioRxiv : the preprint server for biology · 2026Article
- Social attachment shapes interbrain synchrony.bioRxiv : the preprint server for biology · 2026Article
- Social compatibility in opposite-sex prairie vole pairs is modulated by early-life sleep experience.PLoS biology · 2026Article
- Neurotype matching in monogamous rodents is modulated by early-life sleep experience.bioRxiv : the preprint server for biology · 2025Article
- Oxytocin receptors mediate social selectivity in prairie vole peer relationships.Current biology : CB · 2025Article
- Behavioral sex differences in the developmental emergence and selectivity of partner preferences in prairie voles.Hormones and behavior · 2025Article
- Opposite-sex pairing alters social-induced GCaMP and dopamine activity in the insula of male prairie voles.Annals of the New York Academy of Sciences · 2025Article
- Single nucleus RNA-sequencing reveals transcriptional synchrony across different relationships.bioRxiv : the preprint server for biology · 2024Article
- Aging leads to sex-dependent effects on pair bonding and increased number of oxytocin-producing neurons in monogamous prairie voles.Hormones and behavior · 2024Article
- Prairie voles seek social contact with peer companions during immune challenge.Hormones and behavior · 2024Article
- Effects of oxytocin receptor agonism on acquisition and expression of pair bonding in male prairie voles.Translational psychiatry · 2024Article
- Effects of Oxytocin Receptor Agonism on Acquisition and Expression of Pair Bonding in Male Prairie Voles.Research square · 2024Article
- Prairie voles as a model for adaptive reward remodeling following loss of a bonded partner.Annals of the New York Academy of Sciences · 2024Review
- Nucleus accumbens dopamine release reflects the selective nature of pair bonds.Current biology : CB · 2024Article
- Prairie vole pair bonding and plasticity of the social brain.Trends in neurosciences · 2023Article
- Article
- Deepening the understanding of social bonding and dynamics of social interactions.Genes, brain, and behavior · 2022Article
- Emergent intra-pair sex differences and organized behavior in pair bonded prairie voles (Microtus ochrogaster).Genes, brain, and behavior · 2022Article
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Authors and funding
9 authors at 2 institutions in 1 country.
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Abstract
In pair bonding animals, coordinated behavior between partners is required for the pair to accomplish shared goals such as raising young. Despite this, experimental designs rarely assess the behavior of both partners within a bonded pair. Thus, we lack an understanding of the interdependent behavioral dynamics between partners that likely facilitate relationship success. To identify intra-pair behavioral correlates of pair bonding, we used socially monogamous prairie voles (Microtus ochrogaster) and tested both partners using social choice and non-choice tests at short- and long-term pairing timepoints. Females developed a preference for their partner more rapidly than males, with preference driven by different behaviors in each sex. Further, as bonds matured, intra-pair behavioral sex differences and organized behavior emerged-females consistently huddled more with their partner than males did regardless of overall intra-pair affiliation levels. When animals were allowed to freely interact with a partner or a novel vole in sequential free interaction tests, pairs spent more time interacting together than either animal did with a novel vole, consistent with partner preference in the more commonly employed choice test. Total pair interaction in freely moving voles was correlated with female, but not male, behavior. Via a social operant paradigm, we found that pair-bonded females, but not males, are more motivated to access and huddle with their partner than a novel vole. Together, our data indicate that as pair bonds mature, sex differences and organized behavior emerge within pairs, and that these intra-pair behavioral changes are likely organized and driven by the female animal.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.