Evidence map›Paper›PMID 35043688›Full record

ArticleJournal of the American Heart Association2022

Carotid Atherosclerosis Predicts Blood Pressure Control in Patients With Hypertension: The Campania Salute Network Registry.

Costantino Mancusi, Maria Virginia Manzi, Giovanni de Simone, Carmine Morisco, Maria Lembo, Emanuele Pilato, Raffaele Izzo, Valentina Trimarco, Nicola De Luca, Bruno Trimarco

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Abdominal Aorta Remodeling in Hypertensive Patients: The Campania Salute Network.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025
    Article
  4. Article
  5. Atherosclerosis: A Comprehensive Review of Molecular Factors and Mechanisms.International journal of molecular sciences · 2025
    Review
  6. Article
  7. Article
  8. Prolonged Time-to-antihypertensive Therapy Worsens Organ Damage and Blood Pressure Control in Arterial Hypertension.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024
    Observational
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Costantino MancusiDepartment of Advanced Biomedical Sciences Federico II University Naples Italy.
Maria Virginia ManziDepartment of Advanced Biomedical Sciences Federico II University Naples Italy.ORCID 0000-0002-1979-7131
Giovanni de SimoneDepartment of Advanced Biomedical Sciences Federico II University Naples Italy.
Carmine MoriscoDepartment of Advanced Biomedical Sciences Federico II University Naples Italy.
Maria LemboDepartment of Advanced Biomedical Sciences Federico II University Naples Italy.
Emanuele PilatoDepartment of Advanced Biomedical Sciences Federico II University Naples Italy.
Raffaele IzzoDepartment of Advanced Biomedical Sciences Federico II University Naples Italy.ORCID 0000-0002-0308-2836
Valentina TrimarcoDepartment of Neurosciences Federico II University Naples Italy.
Nicola De LucaDepartment of Advanced Biomedical Sciences Federico II University Naples Italy.
Bruno TrimarcoDepartment of Advanced Biomedical Sciences Federico II University Naples Italy.
Federico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The 2018 European Society of Cardiology/European Society of Hypertension arterial hypertension guidelines do not recommend routine carotid ultrasound as a tool to identify hypertension-mediated organ damage, unless clinically indicated. However, carotid plaque (CP) is a strong correlate of increased arterial stiffness, which influences blood pressure (BP) control over time. Thus, we assessed whether evidence of CP at first visit could predict BP control during follow-up. Methods and Results From the CSN (Campania Salute Network) Registry, 6684 patients with hypertension had complete carotid ultrasound examination and were categorized by the presence of CP at baseline. Optimal BP control was defined as average BP <140/90 mm Hg and <135/85 during follow-up for office and home BP, respectively. At baseline, participants with CP (n=3061) were more likely to be men, to be older, to have diabetes, and to exhibit higher systolic BP, lower diastolic BP, worse lipid profile, and higher prevalence of left ventricular hypertrophy (all

Indexed as

Carotid Artery DiseasesHypertensionPlaque, AtheroscleroticBlood PressureHumansHypertrophy, Left VentricularMaleRegistriesatherosclerosishigh blood pressureultrasoundvascular disease

Identifiers

PMID35043688
PMCPMC9075070
OpenAlexW4206021942

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.