Evidence map›Paper›PMID 35043677›Full record

ArticleJournal of the American Heart Association2022

Chronic Covert Brain Infarctions and White Matter Hyperintensities in Patients With Stroke, Transient Ischemic Attack, and Stroke Mimic.

Alessandra Epstein, Marina Schilter, Jan Vynckier, Johannes Kaesmacher, Adnan Mujanovic, Adrian Scutelnic, Morin Beyeler, Nebiyat Filate Belachew, Lorenz Grunder, Marcel Arnold and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Alessandra EpsteinDepartment of Neurology Inselspital Bern University Hospital, and University of Bern Switzerland.
Marina SchilterDepartment of Neurology Inselspital Bern University Hospital, and University of Bern Switzerland.
Jan VynckierDepartment of Neurology Inselspital Bern University Hospital, and University of Bern Switzerland.ORCID 0000-0001-5338-961X
Johannes KaesmacherUniversity Institute for Diagnostic and Interventional Neuroradiology Inselspital Bern University Hospital, and University of Bern Switzerland.ORCID 0000-0002-9177-2289
Adnan MujanovicDepartment of Neurology Inselspital Bern University Hospital, and University of Bern Switzerland.ORCID 0000-0002-6839-7134
Adrian ScutelnicDepartment of Neurology Inselspital Bern University Hospital, and University of Bern Switzerland.ORCID 0000-0001-9053-584X
Morin BeyelerDepartment of Neurology Inselspital Bern University Hospital, and University of Bern Switzerland.ORCID 0000-0001-5911-7957
Nebiyat Filate BelachewUniversity Institute for Diagnostic and Interventional Neuroradiology Inselspital Bern University Hospital, and University of Bern Switzerland.ORCID 0000-0001-5285-5922
Lorenz GrunderUniversity Institute for Diagnostic and Interventional Radiology Inselspital Bern University Hospital, and University of Bern Switzerland.ORCID 0000-0003-0511-8422
Marcel ArnoldDepartment of Neurology Inselspital Bern University Hospital, and University of Bern Switzerland.
David Julian SeiffgeDepartment of Neurology Inselspital Bern University Hospital, and University of Bern Switzerland.ORCID 0000-0003-3890-3849
Simon JungDepartment of Neurology Inselspital Bern University Hospital, and University of Bern Switzerland.
Urs FischerDepartment of Neurology Inselspital Bern University Hospital, and University of Bern Switzerland.ORCID 0000-0003-0521-4051
Thomas Raphael MeinelDepartment of Neurology Inselspital Bern University Hospital, and University of Bern Switzerland.ORCID 0000-0002-0647-9273
University of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background This study was conducted to compare frequencies of chronic brain infarctions (CBIs) and white matter hyperintensities (WMHs) as well as their associations with established early recurrence risk scores in patients with transient ischemic attack (TIA) and stroke mimics compared with ischemic stroke. Methods and Results Single-center cohort study including consecutive patients with TIA, stroke mimics, and acute ischemic stroke, with available magnetic resonance imaging from January 2015 to December 2017. Blinded raters adjudicated WMH (age-related white matter changes score) and CBI according to established definitions. A total of 2112 patients (median [Q1-Q3] age 71 [59-80] years, 43% women, National Institutes of Health Stroke Scale score of 2 [1-7], 80% ischemic stroke, 18% TIA, 2% stroke mimics) were included. While CBIs were present in only 10% of patients with stroke mimic, they were detected in 28% of TIAs and 38% of ischemic strokes (

Indexed as

Ischemic Attack, TransientIschemic StrokeLeukoaraiosisStrokeWhite MatterAgedBrain InfarctionCohort StudiesFemaleHumansMagnetic Resonance ImagingMaleProspective StudiesRisk Factorscovert brain infarctionischemic strokestroke mimictransient ischemic attackwhite matter hyperintensities

Identifiers

PMID35043677
PMCPMC9238476
OpenAlexW4205179861

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.