Evidence map›Paper›PMID 35043655›Full record

ArticleJournal of the American Heart Association2022

Bacteriophages Combined With Subtherapeutic Doses of Flucloxacillin Act Synergistically Against

Jonathan Save, Yok-Ai Que, José M Entenza, Camille Kolenda, Frédéric Laurent, Grégory Resch

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

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  12. The Application of Rat Models inPathogens (Basel, Switzerland) · 2024
    Review
  13. Article
  14. Review
  15. Vancomycin Resistance inMicroorganisms · 2022
    Review
  16. Article
  17. Article
  18. Review
  19. Bacteriophage Therapy forFrontiers in cellular and infection microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jonathan SaveCentre for Research and Innovation in Clinical Pharmaceutical Sciences Lausanne University Hospital Lausanne Switzerland.ORCID 0000-0003-4556-6756
Yok-Ai QueDepartment of Intensive Care Medicine Inselspital, Bern University Hospital, University of Bern Bern Switzerland.ORCID 0000-0001-9443-6101
José M EntenzaDepartment of Fundamental Microbiology University of Lausanne Lausanne Switzerland.
Camille KolendaBacteriology Department, Institute for Infectious Agents French National Reference Centre for Staphylococci, Croix-Rousse University Hospital Hospices Civils de Lyon, Lyon France.
Frédéric LaurentBacteriology Department, Institute for Infectious Agents French National Reference Centre for Staphylococci, Croix-Rousse University Hospital Hospices Civils de Lyon, Lyon France.
Grégory ReschCentre for Research and Innovation in Clinical Pharmaceutical Sciences Lausanne University Hospital Lausanne Switzerland.ORCID 0000-0003-2341-4591
Université Claude Bernard Lyon 1 · FRUniversity of Bern · CHUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The potential of phage therapy for the treatment of endovascular

Indexed as

BacteriophagesEndocarditisEndocarditis, BacterialStaphylococcal InfectionsAnimalsAnti-Bacterial AgentsFloxacillinRatsStaphylococcus aureusAnti-Bacterial AgentsFloxacillinendocarditisphage antibiotic synergismphage therapyStaphylococcus aureus

Identifiers

PMID35043655
PMCPMC9238497
OpenAlexW4205164344

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.