ArticleJournal of biomedical optics2022
Kernel Flow: a high channel count scalable time-domain functional near-infrared spectroscopy system.
Article in Journal of biomedical optics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05752981 (Full-head Coverage Multi-channel Time-resolved Functional Near Infrared Spectroscopy for Early Detection and Prevention of Perioperative Brain Injury), which is not on this map. Cited by 33 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Full-head Coverage Multi-channel Time-resolved Functional Near Infrared Spectroscopy for Early Detection and Prevention of Perioperative Brain Injury
Who cites it
33 citing papers in PubMed.
- Change in brain asymmetry reflects level of acute alcohol intoxication and impacts on inhibitory control.Scientific reports · 2023Trial
- NIRSLINK: A Modular Cascaded Wearable Near-Infrared Spectroscopy System for High-Speed Multi-Site Hemodynamic Monitoring.Biosensors · 2026Article
- SNIRF2BIDS: a GUI-based tool for converting functional near-infrared spectroscopy data to the Brain Imaging Data Structure in R.Neurophotonics · 2026Article
- Surface-based image reconstruction optimization for high-density functional near-infrared spectroscopy.Neurophotonics · 2026Article
- Wearable frequency-domain near-infrared spectroscopy (FD-NIRS) system.Biomedical optics express · 2026Article
- Temporal Changes in Brain Light Scattering and Its Independent Variables Within 2 Days of Life.Biosensors · 2025Article
- Near-infrared time-resolved spectroscopy reveals task-induced emotions by measuring cerebral blood oxygenation changes in the frontal pole during creative activity using a real object.IBRO neuroscience reports · 2025Article
- "hDOS": an automated hybrid diffuse optical device for real-time noninvasive tissue monitoring: precision andJournal of biomedical optics · 2025Article
- High-density multidistance fNIRS enhances detection of brain activity during a word-color Stroop task.Neurophotonics · 2025Article
- Fundamental effects of array density and modulation frequency on image quality of diffuse optical tomography.Medical physics · 2025Article
- Analytical sensitivity factors from distributions of time of flight of photons for near-infrared spectroscopy studies in multilayered turbid media.https://pubmed.ncbi.nlm.nih.gov/39845728/Journal of biomedical optics · 2025Article
- A compact time-domain diffuse optical tomography system for cortical neuroimaging.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- From lab to life: challenges and perspectives of fNIRS for haemodynamic-based neurofeedback in real-world environments.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Investigating the effect of limited spectral information on NIRS-derived changes in hemoglobin and cytochrome-c-oxidase concentration with a diffusion-based model.Biomedical optics express · 2024Article
- How the heterogeneity of the severely injured brain affects hybrid diffuse optical signals: case examples and guidelines.Neurophotonics · 2024Article
- NiReject: toward automated bad channel detection in functional near-infrared spectroscopy.Neurophotonics · 2024Article
- ninjaNIRS: an open hardware solution for wearable whole-head high-density functional near-infrared spectroscopy.Biomedical optics express · 2024Article
- Customizable optode attachments to improve hair clearance timing and inclusiveness in functional near-infrared spectroscopy research.Neurophotonics · 2024Article
- Reliability of brain metrics derived from a Time-Domain Functional Near-Infrared Spectroscopy System.Scientific reports · 2024Article
- Assessing changes in regional cerebral hemodynamics in adults with a high-density full-head coverage time-resolved near-infrared spectroscopy device.Journal of biomedical optics · 2024Article
Corrections and comments
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Authors and funding
30 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
significanceTime-domain functional near-infrared spectroscopy (TD-fNIRS) has been considered as the gold standard of noninvasive optical brain imaging devices. However, due to the high cost, complexity, and large form factor, it has not been as widely adopted as continuous wave NIRS systems.
aimKernel Flow is a TD-fNIRS system that has been designed to break through these limitations by maintaining the performance of a research grade TD-fNIRS system while integrating all of the components into a small modular device. APPROACH: The Kernel Flow modules are built around miniaturized laser drivers, custom integrated circuits, and specialized detectors. The modules can be assembled into a system with dense channel coverage over the entire head.
resultsWe show performance similar to benchtop systems with our miniaturized device as characterized by standardized tissue and optical phantom protocols for TD-fNIRS and human neuroscience results.
conclusionsThe miniaturized design of the Kernel Flow system allows for broader applications of TD-fNIRS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.