Evidence map›Paper›PMID 35043401›Full record

ArticleJournal of the science of food and agriculture2022

Molecular encapsulation and bioactivity of gnetol, a resveratrol analogue, for use in foods.

Silvia Navarro-Orcajada, Irene Conesa, Adrián Matencio, Francisco García-Carmona, José Manuel López-Nicolás

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the science of food and agriculture, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Resveratrol Mitigates Metabolism in Human Microglia Cells.Antioxidants (Basel, Switzerland) · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Silvia Navarro-OrcajadaDepartamento de Bioquímica y Biología Molecular-A, Facultad de Biología, Universidad de Murcia - Regional Campus of International Excellence "Campus Mare Nostrum", Murcia, Spain.ORCID https://orcid.org/0000-0002-1585-1129
Irene ConesaDepartamento de Bioquímica y Biología Molecular-A, Facultad de Biología, Universidad de Murcia - Regional Campus of International Excellence "Campus Mare Nostrum", Murcia, Spain.
Adrián MatencioDipartimento Di Chimica, Università di Torino, Turin, Italy.ORCID https://orcid.org/0000-0001-8203-0673
Francisco García-CarmonaDepartamento de Bioquímica y Biología Molecular-A, Facultad de Biología, Universidad de Murcia - Regional Campus of International Excellence "Campus Mare Nostrum", Murcia, Spain.
José Manuel López-NicolásDepartamento de Bioquímica y Biología Molecular-A, Facultad de Biología, Universidad de Murcia - Regional Campus of International Excellence "Campus Mare Nostrum", Murcia, Spain.ORCID https://orcid.org/0000-0003-0944-3994
Universidad de Murcia · ESUniversity of Turin · IT

Funding

Fundación Séneca 19893/GERM/15Fundación Séneca 21229/PD/19Fundación Séneca 21269/FPI/19Ministerio de Ciencia e Innovación AGL2017-86526-P
6 · The paper itself

Abstract

backgroundGnetol is a stilbene whose characterization and bioactivity have been poorly studied. It shares some bioactivities with its analogue resveratrol, such as anti-inflammatory, anti-thrombotic, cardioprotective and anti-cancer activities. However, the low solubility of stilbenes may limit their potential applications in functional foods. Encapsulation in cyclodextrins could be a solution.

resultsThe antioxidant activity of gnetol was evaluated by 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical cation and ferric reducing antioxidant power methods (Trolox equivalents 13.48 μmol L

conclusionThese results could increase interest of gnetol as an alternative to the most studied stilbene, resveratrol, as well as aid in the development of more stable inclusion complexes that improve its aqueous solubility and stability so that it can be incorporated into functional foods. © 2022 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

CyclodextrinsStilbenesAntioxidantsResveratrolSolubility2,3',5',6-tetrahydroxy-trans-stilbeneAntioxidantsCyclodextrinsResveratrolStilbenesantioxidantcyclodextrinencapsulationfluorescencegnetolstilbenes

Identifiers

PMID35043401
PMCPMC9303806
OpenAlexW4206760937

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.