Evidence map›Paper›PMID 35043356›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2022

Questionnaire-based survey on the prevalence of medication-overuse headache in Japanese one city-Itoigawa study.

Masahito Katsuki, Chinami Yamagishi, Yasuhiko Matsumori, Akihito Koh, Shin Kawamura, Kenta Kashiwagi, Tomohiro Kito, Akio Entani, Toshiko Yamamoto, Takashi Ikeda and 1 more

Abstract read
In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Awareness of medication-overuse headache in Hail, Saudi Arabia.Journal of family medicine and primary care · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Masahito KatsukiDepartment of Neurosurgery, Itoigawa General Hospital, Itoigawa, Niigata, 941-0006, Japan. ktk1122nigt@gmail.com.ORCID http://orcid.org/0000-0002-0192-5430
Chinami YamagishiDepartment of Health Promotion, Itoigawa City, Itoigawa, Niigata, 941-8501, Japan.
Yasuhiko MatsumoriSendai Headache and Neurology Clinic, Sendai, Miyagi, 982-0014, Japan.
Akihito KohDepartment of Neurosurgery, Itoigawa General Hospital, Itoigawa, Niigata, 941-0006, Japan.
Shin KawamuraDepartment of Neurosurgery, Itoigawa General Hospital, Itoigawa, Niigata, 941-0006, Japan.
Kenta KashiwagiDepartment of Neurology, Itoigawa General Hospital, Itoigawa, Niigata, 941-0006, Japan.
Tomohiro KitoDepartment of Neurosurgery, Nou National Health Insurance Clinic, Itoigawa, Niigata, 949-1331, Japan.
Akio EntaniDepartment of Internal Medicine, Itoigawa General Hospital, Itoigawa, Niigata, 941-0006, Japan.
Toshiko YamamotoDepartment of Nursing, Itoigawa General Hospital, Itoigawa, Niigata, 941-0006, Japan.
Takashi IkedaDepartment of Health Promotion, Itoigawa City, Itoigawa, Niigata, 941-8501, Japan.
Fuminori YamagishiDepartment of Surgery, Itoigawa General Hospital, Itoigawa, Niigata, 941-0006, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe medication-overuse headache (MOH) prevalence has not been investigated in a general Japanese population. We performed questionnaire-based survey and revealed MOH prevalence and its characteristics. We also performed clustering to obtain insight for MOH subgrouping.

methodsIn this cross-sectional study, the 15-64-year-old population was investigated in Itoigawa during their COVID-19 vaccination under the national policy. MOH was defined as ≥ 15 days/month plus self-report of use of pain medications ≥ 10 or 15 days/month in the last 3 months. Ward method and k-means +  + were used to perform clustering MOH patients.

resultsAmong 5865 valid responses, MOH prevalence was 2.32%. MOH was common among females and the middle-aged. Combination-analgesic is the most overused as 50%. MOH had aggravation by routine physical activity, moderate or severe pain, and migraine-like, compared to non-MOH. The 136 MOH patients could be grouped into 3 clusters. Age and frequency of acute medication use were essential factors for clustering.

conclusionsThis is the first study of MOH prevalence in Japan. Most MOH characteristics were similar to previous reports worldwide. Public awareness of proper headache treatment knowledge is still needed. Clustering results may be important for subtype grouping from a social perspective apart from existing clinical subtypes.

Indexed as

COVID-19Headache Disorders, SecondaryAdolescentAdultAnalgesicsCOVID-19 VaccinesCross-Sectional StudiesFemaleHeadacheHumansJapanMiddle AgedPrevalenceSurveys and QuestionnairesYoung AdultAnalgesicsCOVID-19 VaccinesArtificial intelligence (AI)Chronic headacheClusteringEpidemiologyMedication-overuse headache (MOH)Migraine

Identifiers

PMID35043356
PMCPMC8765819

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.