Evidence map›Paper›PMID 35043284›Full record

ArticleInternational journal of clinical oncology2022

The role of folate receptor-positive circulating tumor cell analysis in the diagnosis of colorectal cancer: a retrospective cohort study.

Su Yan, Wenyi Guo, Yanliang Liu, Kai Li, Weixing Wang

Abstract read
PubMed Publisher
In one paragraph

Article in International journal of clinical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Su Yan *Department of General Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Wenyi Guo *Department of General Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Yanliang LiuDepartment of General Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Kai LiDepartment of General Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Weixing WangDepartment of General Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China. sate.llite@163.com.ORCID http://orcid.org/0000-0002-3854-0083
Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the application value of folate receptor-positive circulating tumor cell analysis (FR

methodsClinical data of CRC patients and healthy subjects admitted to our hospital from January 2019 to October 2019 were retrospectively collected. CTC result and serological and pathological outcomes of the study patients were collected and analyzed. Receiver operating characteristic curve (ROC curve) was drawn.

resultsThe CTC levels of cancer patients (9.34 ± 3.53 FU/3 ml) were significantly higher than those of healthy subjects (7.00 ± 2.33 FU/3 ml). CTC levels could be related to cancer stage and metastasis in patients. ROC curves were drawn and the area under the ROC curve (AUC) was 0.702. The cutoff value was determined to be 8.87 FU/3 ml. At this cutoff value, the sensitivity and specificity of FR

conclusionFR

Indexed as

Colorectal NeoplasmsNeoplastic Cells, CirculatingBiomarkers, TumorFolic AcidHumansNeoplasm StagingRetrospective StudiesROC CurveBiomarkers, TumorFolic AcidCirculating tumor cellsColorectal cancerDiagnosisFolate receptor

Identifiers

PMID35043284
OpenAlexW4205286858

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.