Evidence map›Paper›PMID 35043264›Full record

ReviewHeart failure reviews2022

Detection of myocardial fibrosis by speckle-tracking echocardiography: from prediction to clinical applications.

Matteo Lisi, Matteo Cameli, Giulia Elena Mandoli, Maria Concetta Pastore, Francesca Maria Righini, Flavio D'Ascenzi, Marta Focardi, Andrea Rubboli, Sergio Mondillo, Michael Y Henein

Abstract readReview
PubMed Publisher
In one paragraph

Review in Heart failure reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

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  20. Cardiovascular Structural and Functional Parameters in Idiopathic Pulmonary Fibrosis at Disease Diagnosis.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Matteo LisiDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy. matteo.lisi@hotmail.it.
Matteo CameliDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy.
Giulia Elena MandoliDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy.
Maria Concetta PastoreDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy.
Francesca Maria RighiniDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy.
Flavio D'AscenziDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy.
Marta FocardiDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy.
Andrea RubboliDepartment of Cardiovascular Disease - AUSL Romagna, Division of Cardiology, Ospedale S. Maria Delle Croci, Viale Randi 5, 48121, Ravenna, Italy.
Sergio MondilloDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy.
Michael Y HeneinDepartment of Public Health and Clinical Medicine, Umeå University and Heart Centre, Umeå, Sweden.
University of Siena · ITOspedale "Santa Maria delle Croci" di Ravenna · ITUmeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial fibrosis (MF) represents the underlying pathologic condition of many cardiac disease, leading to cardiac dysfunction and heart failure (HF). Biopsy studies have shown the presence of MF in patients with decompensating HF despite apparently normal cardiac function. In fact, basic indices of left ventricular (LV) function, such as LV ejection fraction (EF), fail to recognize subtle LV dysfunction caused by MF. Cardiac magnetic resonance (CMR) with late gadolinium enhancement (LGE) is currently recognized as the gold standard imaging investigation for the detection of focal and diffuse cardiac chambers MF; however, its use is limited by its availability and the use of contrast agents, while echocardiography remains the first level cardiac imaging technique due to its low cost, portability and high accessibility. Advanced echocardiographic techniques, above all speckle-tracking echocardiography (STE), have demonstrated reliability for early detection of structural myocardial abnormalities and for the prediction of prognosis in acute and chronic HF. Myocardial strain of both ventricles and also left atrium has been shown to correlate with the degree of MF, providing useful prognostic information in several diseases, such as HF, cardiomyopathies and valvular heart disease. This paper aims to provide an overview of the pathophysiology of MF and the clinical application of STE for the prediction of left and right heart chambers MF in HF patients.

Indexed as

CardiomyopathiesHeart DiseasesHeart FailureVentricular Dysfunction, LeftContrast MediaEchocardiographyFibrosisGadoliniumHumansMagnetic Resonance Imaging, CineReproducibility of ResultsVentricular Function, LeftContrast MediaGadoliniumFibrosisHeart failureMyocardialSpeckle tracking

Identifiers

PMID35043264
OpenAlexW4205338783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.