ArticleAmino acids2022
Detection of impurities in dietary supplements containing L-tryptophan.
Article in Amino acids, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Dual-Functional CeOMolecules (Basel, Switzerland) · 2026Article
- De novo NADCommunications biology · 2025Article
- Simultaneous determination of L-tryptophan impurities in meat products.Amino acids · 2023Article
- Analytical Chemistry of Impurities in Amino Acids Used as Nutrients: Recommendations for Regulatory Risk Management.Nutrients · 2022Review
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Authors and funding
5 authors.
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Abstract
Impurities in nine dietary supplements containing L-tryptophan were evaluated using an HPLC methodology. In five tested products, the total impurities were higher than the thresholds described in the Food Chemical Codex or implemented in the EU for pharmaceutical grade L-tryptophan. In addition, liquid chromatography-mass spectrometry was used to specifically test for the presence of 1,1'-ethylidenebis-L-tryptophan (EBT). None of the tested products contained detectable amounts of EBT. High amounts of unidentified impurities in some dietary supplements point to potential health risks.
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