Evidence map›Paper›PMID 35043120›Full record

ArticlemedRxiv : the preprint server for health sciences2022

Extremely potent monoclonal antibodies neutralize Omicron and other SARS-CoV-2 variants.

Zhaochun Chen, Peng Zhang, Yumiko Matsuoka, Yaroslav Tsybovsky, Kamille West, Celia Santos, Lisa F Boyd, Hanh Nguyen, Anna Pomerenke, Tyler Stephens and 13 more

Open access · greenAbstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 14 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 3 institutions in 1 country.

Zhaochun Chen
Peng Zhang
Yumiko Matsuoka
Yaroslav Tsybovsky
Kamille West
Celia Santos
Lisa F Boyd
Hanh Nguyen
Anna Pomerenke
Tyler Stephens
Adam S Olia
Valeria De Giorgi
Michael R Holbrook
Robin Gross
Elena Postnikova
Nicole L Garza
Reed F Johnson
David H Margulies
Peter D Kwong
Harvey J Alter
Ursula J Buchholz
Paolo Lusso
Patrizia Farci
National Institutes of Health · USNational Institutes of Health Clinical Center · USLeidos (United States) · US

Funding

Molecular Genetic Analysis Of Lymphocyte FunctionZIAAI000394 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MARGULIES, DAVID · 2009 to 2025
$11.5M
SARS-CoV-2 Virology CoreZICAI001321 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI ARORA, GUNJAN · 2020 to 2025
$5.8M
Generation of Neutralizing Monoclonal Antibodies Against SARS-CoV-2 for Prevention and Therapy in Patients with COVID-19ZIAAI001304 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI FARCI, PATRIZIA · 2020 to 2023
$214k
Recombinant Engineering of SARS-CoV-2 Spike and N proteinsZIAAI001267 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MARGULIES, DAVID · 2020 to 2023
$185k
6 · The paper itself

Abstract

The ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has triggered a devastating global health, social and economic crisis. The RNA nature and broad circulation of this virus facilitate the accumulation of mutations, leading to the continuous emergence of variants of concern with increased transmissibility or pathogenicity

Identifiers

PMID35043120
PMCPMC8764729
OpenAlexW4206169915

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.