Evidence map›Paper›PMID 35043013›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2022

Lack of TRPV1 aggravates obesity-associated hypertension through the disturbance of mitochondrial Ca2+ homeostasis in brown adipose tissue.

Li Li, Liqun Ma, Zhidan Luo, Xiao Wei, Yu Zhao, Cui Zhou, Aidi Mou, Zongshi Lu, Mei You, Chengkang He and 7 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  5. Review
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  9. Calcium signaling in mitochondrial intermembrane space.Biochemical Society transactions · 2024
    Review
  10. MCU genetically altered mice suggest how mitochondrial CaTrends in endocrinology and metabolism: TEM · 2024
    Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Thermoreceptor TRPV1 regulates body weight and blood pressure in the absence of thermogenin.Hypertension research : official journal of the Japanese Society of Hypertension · 2022
    Article
  17. Review
  18. Nanoparticles-Mediated Modulation of TRP Channels: Advances and Therapeutic Potential.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Li LiCenter for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Daping Hospital, The Army Medical University, Chongqing Institute of Hypertension, Chongqing, 400042, China.
Liqun MaCenter for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Daping Hospital, The Army Medical University, Chongqing Institute of Hypertension, Chongqing, 400042, China.
Zhidan LuoCenter for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Daping Hospital, The Army Medical University, Chongqing Institute of Hypertension, Chongqing, 400042, China.
Xiao WeiCenter for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Daping Hospital, The Army Medical University, Chongqing Institute of Hypertension, Chongqing, 400042, China.
Yu ZhaoCenter for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Daping Hospital, The Army Medical University, Chongqing Institute of Hypertension, Chongqing, 400042, China.
Cui ZhouCenter for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Daping Hospital, The Army Medical University, Chongqing Institute of Hypertension, Chongqing, 400042, China.
Aidi MouCenter for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Daping Hospital, The Army Medical University, Chongqing Institute of Hypertension, Chongqing, 400042, China.
Zongshi LuCenter for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Daping Hospital, The Army Medical University, Chongqing Institute of Hypertension, Chongqing, 400042, China.
Mei YouCenter for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Daping Hospital, The Army Medical University, Chongqing Institute of Hypertension, Chongqing, 400042, China.
Chengkang HeCenter for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Daping Hospital, The Army Medical University, Chongqing Institute of Hypertension, Chongqing, 400042, China.
Huan MaCenter for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Daping Hospital, The Army Medical University, Chongqing Institute of Hypertension, Chongqing, 400042, China.
Qing ZhouCenter for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Daping Hospital, The Army Medical University, Chongqing Institute of Hypertension, Chongqing, 400042, China.
Lijuan WangCenter for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Daping Hospital, The Army Medical University, Chongqing Institute of Hypertension, Chongqing, 400042, China.
Tingbing CaoCenter for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Daping Hospital, The Army Medical University, Chongqing Institute of Hypertension, Chongqing, 400042, China.
Yucun GuThe Regenerative Medicine Center, Aston Medical School, Aston University, Birmingham, UK.
Peng GaoCenter for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Daping Hospital, The Army Medical University, Chongqing Institute of Hypertension, Chongqing, 400042, China.
Zhiming ZhuCenter for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Daping Hospital, The Army Medical University, Chongqing Institute of Hypertension, Chongqing, 400042, China. zhuzm@yahoo.com.
Army Medical University · CNDaping Hospital · CNAston University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The combination of obesity and hypertension is associated with high morbidity and mortality; however, the mechanism underlying obesity-induced hypertension remains unclear. In this study, we detected the possible effects of TRPV1, a previously identified antihypertensive calcium (Ca

Indexed as

Adipose Tissue, BrownHypertensionAnimalsCalciumHomeostasisMiceMice, Inbred C57BLMice, KnockoutObesityTRPV Cation ChannelsCalciumTRPV1 protein, mouseTRPV Cation ChannelsBrown adipose tissueLeucine zipper-EF-hand containing transmembrane protein 1Mitochondrial Ca2+Obesity-associated hypertensionTransient receptor potential vanilloid-1Uncoupling protein 1

Identifiers

PMID35043013
PMCPMC9010289
OpenAlexW4206690379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.