ArticleScientific reports2022
The impact of COVID-19 on pregnancy outcomes in a diverse cohort in England.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Neonatal outcomes among pregnant women with COVID-19: a systematic scoping review and meta-analysis.BMC pregnancy and childbirth · 2025Pooled it
- Outcomes of SARS-CoV-2 infection in early pregnancy-A systematic review and meta-analysis.Acta obstetricia et gynecologica Scandinavica · 2024Pooled it
- Impacts of COVID-19 pandemic on preterm birth: a systematic review and meta-analysis.Public health · 2022Pooled it
- Temporal trends in pregnancy outcomes during a health system shock.Communications medicine · 2026Article
- Association between COVID-19 outbreak and preterm birth rates in a low-infection cohort from a tertiary Shanghai maternity center: a retrospective study.Frontiers in pediatrics · 2026Article
- Examining the severity of illness in pregnant women infected with COVID-19 during three waves of the disease in Ahvaz, Iran.BMC pregnancy and childbirth · 2025Observational
- The impact of COVID-19 infection on neonatal birth weight and outcomes.Pregnancy (Hoboken, N.J.) · 2025Article
- Do timing and severity of gestational COVID-19 impact perinatal and neonatal outcomes?Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- The prevalence of symptomatic COVID-19 infection among pregnant women and its relationship with pregnancy outcomes: a retrospective review of the medical records in North East Iran.BMC pregnancy and childbirth · 2025Article
- Findings of Reduced Head Circumference with COVID-19 Infection in the Third Trimester: A Retrospective Cohort Study.Biomedicines · 2025Article
- The Serbian version of the Pandemic-Related Pregnancy Stress Scale (PREPS-SRB)-A validation study.PloS one · 2025Article
- A Registry-Based Observational Study on the Maternal and Fetal Outcomes of COVID-19 Patients in Hong Kong.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2024Article
- Social distancing and extremely preterm births in the initial COVID-19 pandemic period.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Evaluation of the effect of COVID-19 infection in pregnancy and puerperium in a suburban medical college in West Bengal, India.Journal of family medicine and primary care · 2024Article
- Poor Response to Gonadotropin Stimulation and Perinatal Outcomes in Fresh In Vitro Fertilization Embryo Transfer Cycles-A Retrospective Cohort Study.Journal of clinical medicine · 2024Article
- Offspring cardiometabolic outcomes and postnatal growth trajectories after exposure to maternal SARS-CoV-2 infection.Obesity (Silver Spring, Md.) · 2024Article
- Assessment of severity and feto-maternal outcomes among COVID-19 infected pregnant females hospitalized at tertiary care center in western Nepal.Annals of medicine and surgery (2012) · 2024Article
- COVID-19 and Pregnancy Outcomes: A Descriptive Study From a Tertiary Hospital in Ras Al Khaimah, UAE.Obstetrics and gynecology international · 2024Article
- Protective potential of mesenchymal stem cells against COVID-19 during pregnancy.Future science OA · 2024Review
- Infection with SARS-CoV-2 during pregnancy and risk of stillbirth: a Scandinavian registry study.BMJ public health · 2023Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is conflicting evidence regarding the effect of coronavirus disease (COVID-19) in pregnancy. Risk factors for COVID-19 overlap with risk factors for pregnancy complications. We aimed to assess the effects of the COVID-19 pandemic and confirmed SARS-CoV-2 infection on pregnancy outcomes. A retrospective interrupted time-series and matched cohort analysis was performed. Singleton pregnancies completed between 1st January 2016 and 31st January 2021 were included. Trends in outcomes were analysed over time. Modelled COVID-19 transmission data were applied to deliveries since 1st January 2020 to assign a risk of COVID-19 to each pregnancy, and incorporated into a regression model of birthweight. Confirmed COVID-19 cases were matched to controls delivered in the pre-pandemic period, and maternal and neonatal outcomes compared. 43,802 pregnancies were included, with 8343 in the model of birthweight. There was no increase in the risk of stillbirth (p = 0.26) or neonatal death (p = 0.64) during the pandemic. There was no association between modelled COVID-19 attack rate (%) in any trimester and birthweight (first trimester p = 0.50, second p = 0.15, third p = 0.16). 214 COVID-positive women were matched to controls. Preterm birth was more common in symptomatic cases (14/62, 22.6%) compared to asymptomatic cases (9/109, 8.3%, p = 0.008) and controls (5/62, 8.1%, p = 0.025). Iatrogenic preterm birth was more common in cases (21/214, 9.8%) than controls (9/214, 4.2%, p = 0.02). All other examined outcomes were similar between groups. There was no significant impact of COVID-19 on the examined birth outcomes available. Symptomatic COVID-19 should be considered a risk factor for preterm birth, possibly due to an increase in iatrogenic deliveries for maternal indications.
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