Evidence map›Paper›PMID 35042977›Full record

ReviewNature reviews. Molecular cell biology2022

Modulation of cellular processes by histone and non-histone protein acetylation.

Maria Shvedunova, Asifa Akhtar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Molecular cell biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 579 papers.

0numbers the graph read from it
0cells of the map it votes in
579citing papers in PubMed
69.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

579 citing papers in PubMed, 850 citations in OpenAlex.

  1. Article
  2. Research progress on lysine acetylation (Review).International journal of molecular medicine · 2026
    Review
  3. Article
  4. Article
  5. Toxoplasma gondii SIR2A Promotes Tachyzoite Invasion via Lysine Deacetylase Activity.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  6. Mechanical regulation of cell memory.Nature structural & molecular biology · 2026
    Review
  7. Review
  8. The histone deacetylase family in health and disease.Signal transduction and targeted therapy · 2026
    Review
  9. Review
  10. Article
  11. Review
  12. Role of HMGB1 in Neuroinflammation.Molecular neurobiology · 2026
    Review
  13. Review
  14. Review
  15. Article
  16. Autophagy modulation in cancer.Nature reviews. Drug discovery · 2026
    Review
  17. Review
  18. Article
  19. Arteriosclerosis, thrombosis, and vascular biology · 2026
    Article
  20. Review

519 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Maria ShvedunovaDepartment of Chromatin Regulation, Max Planck Institute of Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.ORCID http://orcid.org/0000-0003-3761-4535
Asifa AkhtarDepartment of Chromatin Regulation, Max Planck Institute of Immunobiology and Epigenetics, Freiburg im Breisgau, Germany. akhtar@ie-freiburg.mpg.de.ORCID http://orcid.org/0000-0001-8973-6193
Max Planck Institute of Immunobiology and Epigenetics · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lysine acetylation is a widespread and versatile protein post-translational modification. Lysine acetyltransferases and lysine deacetylases catalyse the addition or removal, respectively, of acetyl groups at both histone and non-histone targets. In this Review, we discuss several features of acetylation and deacetylation, including their diversity of targets, rapid turnover, exquisite sensitivity to the concentrations of the cofactors acetyl-CoA, acyl-CoA and NAD

Indexed as

HistonesLysine AcetyltransferasesAcetylationLysineProtein Processing, Post-TranslationalHistonesLysineLysine Acetyltransferases

Identifiers

PMID35042977
OpenAlexW4205702645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.