Evidence map›Paper›PMID 35042508›Full record

ArticleBMC public health2022

Alcohol-attributable burden of cancer in Argentina.

I A T van de Luitgaarden, A E Bardach, N Espinola, I C Schrieks, D E Grobbee, J W J Beulens

Abstract read
In one paragraph

Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

I A T van de LuitgaardenUniversity Medical Center Utrecht, Utrecht University, Julius Global Health, Julius Center for Health Sciences and Primary Care, Huispost Str. 6.131, 3508 GA, Utrecht, the Netherlands. I.A.T.vandeluitgaarden@umcutrecht.nl.
A E BardachInstitute for Clinical Effectiveness and Health Policy, Buenos Aires, Argentina.
N EspinolaInstitute for Clinical Effectiveness and Health Policy, Buenos Aires, Argentina.
I C SchrieksJulius Clinical, Zeist, the Netherlands.
D E GrobbeeUniversity Medical Center Utrecht, Utrecht University, Julius Global Health, Julius Center for Health Sciences and Primary Care, Huispost Str. 6.131, 3508 GA, Utrecht, the Netherlands.
J W J BeulensUniversity Medical Center Utrecht, Utrecht University, Julius Global Health, Julius Center for Health Sciences and Primary Care, Huispost Str. 6.131, 3508 GA, Utrecht, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlcohol consumption is a risk factor for several types of cancer. Alcohol consumption levels in Argentina are among the highest in the world, and malignant neoplasms are the second cause of death in the country. Public health strategies aimed at reducing alcohol consumption could possibly lead to a decrease in cancer burden. Alcohol-attributable burden has been estimated before in neighboring countries Chile and Brazil. We now aimed to quantify the burden for Argentina.

methodsWe obtained data on alcohol consumption levels from a national representative health survey and etiologic effect sizes for the association between alcohol and cancer from the most recent comprehensive meta-analysis. We estimated the number of alcohol-attributable cancer-related deaths and disability-adjusted life years (DALYs), stratified by consumption level (light (0.1-12.5 g/day), moderate (12.6-50 g/day), or heavy (> 50 g/day) drinking). We additionally explored which hypothetical scenario would achieve the highest reduction in alcohol-attributable cancer burden: 1) heavy drinkers shifting to moderate drinking or 2) moderate drinkers shifting to light drinking.

resultsIn 2018, 53% of the Argentinean population consumed alcohol. In men 3.7% of all cancer deaths and DALYs were attributable to alcohol consumption, in women this was 0.8% of all cancer deaths and DALYs. When moderate drinkers would shift to light drinking, 46% of alcohol-attributable cancer deaths and DALYs would be prevented, opposed to only 24% when heavy drinkers would shift to moderate drinking.

conclusionMost cancer deaths and DALYs were attributable to moderate alcohol consumption (50%). This calls for implementation of population-wide strategies-instead of targeting heavy drinking only-to effectively reduce harmful use of alcohol and its impact on disease burden.

Indexed as

Alcohol DrinkingNeoplasmsArgentinaEthanolFemaleHumansMaleQuality-Adjusted Life YearsRisk FactorsEthanol

Identifiers

PMID35042508
PMCPMC8764501

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.