Evidence map›Paper›PMID 35042479›Full record

Observational studyBMC musculoskeletal disorders2022

Percussion test: description and diagnostic accuracy of a new manual test for bone marrow edema of the knee.

Valerio Sansone, Alessandro Galluzzo, Emanuele Maiorano, Marina Benedetta Polatti, Valerio Pascale

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Valerio SansoneDepartment of Orthopaedics, University of Milan, Milan, Italy.
Alessandro GalluzzoResidency Program in Orthopaedics and Traumatology, University of Milan, Milan, Italy.
Emanuele MaioranoI.R.C.C.S. Istituto Ortopedico Galeazzi, Milan, Italy.
Marina Benedetta PolattiUniversity of Milan, Milan, Italy. marinapolatti@libero.it.
Valerio PascaleDepartment of Orthopaedics, University of Milan, Milan, Italy.
Istituto Ortopedico Galeazzi · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrompt diagnosis of bone marrow lesion (BML) is difficult but critical for correct treatment. Magnetic resonance imaging is the gold standard, although expensive and time consuming. Simple and reliable clinical test for BML detection is lacking. Aim of the study is to describe a new manual clinical test called Percussion Test (PT) and to statistically determine its diagnostic accuracy in BML, compared to MRI imaging.

methodsAfter evaluation of the inclusion and exclusion criteria, 218 consecutive patients with unilateral knee pain and age comprised between 18 and 80 years old were enrolled in our observational prospective study. Informed consent was obtained for each patient. After medical history collection, PT was performed by a single operator as described. MRI was performed in the affected knee to detect the presence of BML. Coherence in PT and MRI assessment was evaluated in each quadrant of the knee via contingency tables, as sensitivity, specificity, NPV, PPV and diagnostic accuracy were calculated.

resultsNo correlation with a positive PT was demonstrated for the covariables gender (p = 0.156), age (p = 0.272) and BMI (p = 0.639). PT showed a sensitivity ranging from 60.6 (40.6-80.6) to 79.5 (63.0-96.0) and a specificity ranging from 85.7 (80.0-91.5) to 96.0 (93.1-98.9) depending on knee quadrant. Diagnostic accuracy ranged from 81.6 (75.9-86.6) to 89.4 (84.6-93.2), and p-value was < 0.00001 in a chi-squared analysis for all quadrants.

conclusionsPT showed sensitivity and specificity values that are comparable with other clinical tests routinely adopted in clinical practice. In the absence of other reliable clinical test, PT has the potential to become a useful bedside tool in the diagnosis and management of BMLs.

Indexed as

Bone Marrow DiseasesOsteoarthritis, KneeAdolescentAdultAgedAged, 80 and overBone MarrowEdemaHumansKnee JointMagnetic Resonance ImagingMiddle AgedPercussionProspective StudiesYoung AdultBone edemaBone marrow lesionDiagnostic accuracyKneeKnee painPhysical examinationProspective observational studySensitivity, specificity

Identifiers

PMID35042479
PMCPMC8767745
OpenAlexW4206792506

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.