Evidence map›Paper›PMID 35042469›Full record

ArticleBMC infectious diseases2022

Etiologies of fever of unknown origin in HIV/AIDS patients, Hanoi, Vietnam.

Thu Kim Nguyen, Yen Hai Nguyen, Hao Thi Nguyen, Quang Minh Khong, Ngoc Kim Tran

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Distribution of the causes of fever of unknown origin in China, 2013-2022.Journal of translational internal medicine · 2024
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Thu Kim NguyenHanoi Medical University, Hanoi, Vietnam. nguyenkimthu@hmu.edu.vn.
Yen Hai NguyenHanoi Medical University, Hanoi, Vietnam.
Hao Thi NguyenNational Hospital for Tropical Diseases, Hanoi, Vietnam.
Quang Minh KhongNational Hospital for Tropical Diseases, Hanoi, Vietnam.
Ngoc Kim TranActionAid Vietnam, Hanoi, Vietnam.
Hanoi Medical University · VNHospital for Tropical Diseases · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFever of unknown origin (FUO) is a challenge for clinicians treating patients with HIV/AIDS. CD4 counts can be helpful in the diagnosis and treatment. This study aimed to determine several common etiologies of FUO stratified by CD4 count levels in HIV/AIDS patients.

methodsA cross-sectional retrospective and prospective study was conducted in 195 HIV/AIDS patients with FUO admitted to the National Hospital for Tropical Diseases from January 2016 to June 2019. Clinical parameters, immune status, and etiologies for each patient were recorded. Odds ratios were calculated to compare the distributions of common etiologies in groups with two different CD4 count levels: < 50 cells/mm

resultsThe proportions of opportunistic infections and noninfectious etiologies were 93.3% and 3.6%, respectively. Tuberculosis was the most common opportunistic infection (46.7%), followed by talaromycosis (29.2%) and Pneumocystis jiroveci (PCP) infection (20.5%). Tuberculosis was predominant in all CD4 level groups. Most patients with talaromycosis had CD4 counts below 50 cells/mm

conclusionsOpportunistic infections, especially tuberculosis, are still the leading cause of FUO in HIV/AIDS patients. Tuberculosis and Talaromyces marneffei (TM) infection should be considered in patients with CD4 cell counts < 50 cells/mm

Indexed as

Fever of Unknown OriginHIV InfectionsCD4 Lymphocyte CountCross-Sectional StudiesHumansProspective StudiesRetrospective StudiesVietnamCD4 cell countFever of unknown originHIV/AIDS patientsVietnam

Identifiers

PMID35042469
PMCPMC8764815
OpenAlexW4225477201

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.