Evidence map›Paper›PMID 35042456›Full record

ArticleBMC cancer2022

Radiosynthesis of a novel antisense imaging probe targeting LncRNA HOTAIR in malignant glioma.

Jiongyu Ren, Xiyuan Zhang, Jiang Cao, Jiali Tian, Jin Luo, Yaping Yu, Fengkui Wang, Qian Zhao

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. The multifaceted functions of long non-coding RNAExpert reviews in molecular medicine · 2024
    Review
  5. Review
  6. Review
  7. Nucleic acid drug vectors for diagnosis and treatment of brain diseases.Signal transduction and targeted therapy · 2023
    Review
  8. A novel tetrapeptide for chelator-free radiolabeling in optimized preparation ofAmerican journal of nuclear medicine and molecular imaging · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jiongyu RenDepartment of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, China.
Xiyuan ZhangXiangYa School of Medicine, CSU, Changsha, 410006, China.
Jiang CaoDepartment of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, China.
Jiali TianDepartment of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, China.
Jin LuoDepartment of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, China.
Yaping YuDepartment of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, China.
Fengkui WangDepartment of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, China.
Qian ZhaoDepartment of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, China. cecilia_hh@126.com.
Ningxia Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong non-coding RNA (LncRNA) HOTAIR was amplified and overexpressed in many human carcinomas, which could serve as a useful target for cancer early detection and treatment. The

methodsThe ASON targeting LncRNA HOTAIR as well as mismatched ASON (ASONM) were designed and modified. The radiolabeling of

resultsThe labeling efficiencies of

conclusionThe liposome encapsulated

Indexed as

AnimalsDisease Models, AnimalGliomaHeterograftsLiposomesMiceOligonucleotides, AntisenseOrganotechnetium CompoundsRadiopharmaceuticalsRNA, Long NoncodingTissue DistributionHOTAIR long non-coding RNA, mouseLiposomesOligonucleotides, AntisenseOrganotechnetium CompoundsRadiopharmaceuticalsRNA, Long NoncodingAntisense oligonucleotide probeLncRNA HOTAIRMalignant gliomaSPECT imaging

Identifiers

PMID35042456
PMCPMC8767688
OpenAlexW4221133092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.