Evidence map›Paper›PMID 35042410›Full record

ArticleProceedings. Biological sciences2022

Parasite co-infection: an ecological, molecular and experimental perspective.

Frank Venter, Keith R Matthews, Eleanor Silvester

Open access · hybridAbstract read
In one paragraph

Article in Proceedings. Biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Immunity beyond borders: non-lethalFrontiers in immunology · 2026
    Article
  5. Article
  6. Transboundary and emerging diseases · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Parasitology · 2024
    Article
  12. Review
  13. Review
  14. Cell-cell communication in African trypanosomes.Microbiology (Reading, England) · 2023
    Review
  15. Article
  16. Article
  17. Body condition reveals hidden correlations between co-infection and behavior in sunfish.Behavioral ecology : official journal of the International Society for Behavioral Ecology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Frank VenterInstitute for Immunology and Infection Research, Ashworth Laboratories, School of Biological Sciences, University of Edinburgh, Scotland EH9 3FL, UK.ORCID 0000-0002-1925-2510
Keith R MatthewsInstitute for Immunology and Infection Research, Ashworth Laboratories, School of Biological Sciences, University of Edinburgh, Scotland EH9 3FL, UK.ORCID 0000-0003-0309-9184
Eleanor SilvesterInstitute for Immunology and Infection Research, Ashworth Laboratories, School of Biological Sciences, University of Edinburgh, Scotland EH9 3FL, UK.ORCID 0000-0001-9827-1412
University of Edinburgh · GBUniversity of Cambridge · GB

Funding

Wellcome TrustWellcome Trust 103740/Z/14/ZWellcome Trust 108905/Z/15/ZWellcome Trust 206815/Z/17/ZWellcome Trust 221 717/Z/20/Z
6 · The paper itself

Abstract

Laboratory studies of pathogens aim to limit complexity in order to disentangle the important parameters contributing to an infection. However, pathogens rarely exist in isolation, and hosts may sustain co-infections with multiple disease agents. These interact with each other and with the host immune system dynamically, with disease outcomes affected by the composition of the community of infecting pathogens, their order of colonization, competition for niches and nutrients, and immune modulation. While pathogen-immune interactions have been detailed elsewhere, here we examine the use of ecological and experimental studies of trypanosome and malaria infections to discuss the interactions between pathogens in mammal hosts and arthropod vectors, including recently developed laboratory models for co-infection. The implications of pathogen co-infection for disease therapy are also discussed.

Indexed as

CoinfectionMalariaParasitesTrypanosomaAnimalsHost-Parasite InteractionsMammalsco-infectionparasiteplasmodiumtrypanosoma

Identifiers

PMID35042410
PMCPMC8767208
OpenAlexW4206267951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.