Evidence map›Paper›PMID 35042402›Full record

ArticleOpen biology2022

Kre28-Spc105 interaction is essential for Spc105 loading at the kinetochore.

Babhrubahan Roy, Janice Sim, Simon J Y Han, Ajit P Joglekar

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Babhrubahan RoyCell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA.ORCID 0000-0003-1815-8714
Janice SimCell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA.ORCID 0000-0002-3215-1482
Simon J Y HanCell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA.ORCID 0000-0001-8039-510X
Ajit P JoglekarCell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA.ORCID 0000-0002-0607-5332
University of Michigan · US

Funding

The systems biology of mitotic checkpoint signaling and its relevance to cancer cell biologyR35GM126983 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Ajit Joglekar · 2018 to 2026
$5.1M
Architecture-function analysis of the kinetochore motorR01GM105948 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JOGLEKAR, AJIT · 2013 to 2017
$1.4M
NIGMS NIH HHS R01 GM105948NIGMS NIH HHS R35 GM126983
6 · The paper itself

Abstract

Kinetochore (KTs) are macromolecular protein assemblies that attach sister chromatids to spindle microtubules (MTs) and mediate accurate chromosome segregation during mitosis. The outer KT consists of the KMN network, a protein super-complex comprising

Indexed as

KinetochoresSaccharomyces cerevisiae ProteinsChromosome SegregationMicrotubule-Associated ProteinsMicrotubulesMitosisNuclear ProteinsSaccharomyces cerevisiaeSpindle ApparatusKre28 protein, S cerevisiaeMicrotubule-Associated ProteinsNDC80 protein, S cerevisiaeNuclear ProteinsSaccharomyces cerevisiae ProteinsSpc105 protein, S cerevisiaekinetochoremicrotubulespindle assembly checkpoint

Identifiers

PMID35042402
PMCPMC8767186
OpenAlexW4206486729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.