ArticleInternational journal of cancer2022
Cancer risk and mortality after solid organ transplantation: A population-based 30-year cohort study in Finland.
Article in International journal of cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 5 of them syntheses that pooled it.
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Who cites it
46 citing papers in PubMed, 5 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- Malignancies after vascularized composite allotransplantation.Frontiers in immunology · 2026Pooled it
- Cancer-related mortality among solid organ transplant recipients: systematic review and meta-analysis.Frontiers in transplantation · 2026Pooled it
- De novo colorectal cancer after kidney transplantation: a systematic review and meta-analysis.British journal of cancer · 2025Pooled it
- Incidence of renal cell carcinoma after solid organ transplantation: a systematic review and meta-analysis.BMC urology · 2024Pooled it
- Lung cancer incidences after liver transplantation: A systematic review and meta-analysis.Cancer medicine · 2023Pooled it
- De novo cancer-related mortality after solid organ transplantation in England: the EpCOT study.British journal of cancer · 2026Article
- Skin lesion triage in organ transplant recipients using line-field confocal optical coherence tomography: a retrospective classification study.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026Article
- Cancer Risk After Simultaneous Pancreas-Kidney Transplantation Compared With Kidney Transplant Alone: A Propensity-Matched Cohort Study.Clinical transplantation · 2026Article
- Development and validation of a prognostic nomogram incorporating preoperative NLR, CEA and CA19-9 for overall survival in colorectal cancer.Oncology letters · 2026Article
- Pan-cancer polygenic risk score associates with cancer susceptibility following kidney transplantation.JCI insight · 2026Article
- Human Papillomavirus-Related Cancer in People With HIV and Solid Organ Transplant Recipients.JAMA network open · 2026Article
- Decision-making, regret, and quality of life in living organ donors: a cross-sectional study.Scientific reports · 2026Article
- Skin Cancer in Solid Organ Transplant Recipients: A Review.American journal of clinical dermatology · 2026Review
- Review
- Vascularised Composite Allotransplantation: Emerging Applications in Reconstructive Surgery and Solid Organ Transplantation.Medicina (Kaunas, Lithuania) · 2026Review
- Findings and significance of early follow-up biopsies after treatment of acute rejection in kidney transplant recipients.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Evaluating cancer risk profiles in lung transplant recipients.Translational lung cancer research · 2025Article
- Care of the immunocompromised cancer patient in the perioperative period: Narrative review.Indian journal of anaesthesia · 2025Review
- High linc00473 expression indicated worse cancer prognosis, based on the meta-analysis.Discover oncology · 2025Article
- Whole-exome sequencing of kidney transplant recipients and donors: insights into end-stage renal disease and post-transplant genetic risk.BMC nephrology · 2025Article
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cancer is a significant cause of morbidity and mortality after solid organ transplantation (SOT) and related to lifelong immunosuppression. This retrospective registry study assessed for the first time in Finland population-based cancer risk and cancer mortality after all SOTs (lung and childhood transplantations included) as standardized incidence ratios (SIRs) and standardized mortality ratios (SMRs). Data from transplant registries were linked with the data of Finnish Cancer Registry and Statistics Finland. We followed 6548 consecutive first SOT recipients from 1 January 1987 to 31 December 2016 translating to 66 741 person-years (median follow-up time 8.9 years [interquartile range 4.0-15.1]). In total, 2096 cancers were found in 1483 patients (23% of all patients). Majority of cancers (53%) were nonmelanoma skin cancers (NMSCs). The overall SIR was 3.6 (95% confidence interval [CI]: 3.5-3.8) and the SIR excluding NMSCs was 2.2 (95% CI: 2.0-2.3). SIR for all cancers was highest for heart (5.0) and lowest for liver (2.7) recipients. Most common cancer types after NMSCs were non-Hodgkin lymphoma (NHL), SIR 9.9 (95% CI: 8.5-11.4) and kidney cancer, SIR 7.3 (95% CI: 6.0-8.8). Cancer-related deaths were 17% (n = 408) of all deaths after first month post transplantation. SMR for all cancers was 2.5 (95% CI: 2.2-2.7) and for NHL 13.6 (95% CI: 10.7-16.8). Notably, overall SIR for cancer was lower in later period (2000-2016), 3.0 (95% CI: 2.8-3.2), than in earlier period (1987-1999), 4.3 (95% CI: 4.0-4.5), P < .001. Decrease in cancer incidence was temporally associated with major changes in immunosuppression in the 2000s.
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