Evidence map›Paper›PMID 35041499›Full record

ArticleJournal of bacteriology2022

Expression of the DeaD RNA Helicase Is Regulated at Multiple Levels through Its Long mRNA 5' Untranslated Region.

Sandeep Ojha, Chaitanya Jain

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sandeep OjhaDepartment of Biochemistry and Molecular Biology, University of Miamigrid.26790.3a Miller School of Medicine, Miami, Florida, USA.
Chaitanya JainDepartment of Biochemistry and Molecular Biology, University of Miamigrid.26790.3a Miller School of Medicine, Miami, Florida, USA.
University of Miami · US

Funding

Regulation of Messenger RNA by DEAD-box ProteinsR01GM114540 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI JAIN, CHAITANYA · 2015 to 2018
$1.2M
NIGMS NIH HHS R01 GM114540NIH HHS GM114540
6 · The paper itself

Abstract

DEAD-box proteins (DBPs) are a prominent class of RNA remodeling proteins that alter RNA structure, a process they typically perform through an ATP-dependent RNA helicase activity. Although many DBPs have been characterized at the structural and functional level in detail, much less is known about how they are regulated. We previously showed that the mRNA for the Escherichia coli DeaD DBP contains an unusually long 5' untranslated region (5' UTR) of 838 nucleotides (nt) and that it is the primary RNA determinant of DeaD autoregulation. We speculated that such a long and complex 5' UTR might regulate

Indexed as

DEAD-box RNA HelicasesEscherichia coli Proteins3' Untranslated Regions5' Untranslated RegionsEscherichia coliRNA, Messenger3' Untranslated Regions5' Untranslated RegionsDEAD-box RNA HelicasesEscherichia coli ProteinsRNA, Messenger5′ untranslated regionDeaD-box proteinsregulation of gene expressionRNA helicaseRNA structure

Identifiers

PMID35041499
PMCPMC8923229
OpenAlexW4206259067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.